| |
All trials
|
All trials excluding FMHS
|
Adequately controlled trials
|
Adequately controlled trials excluding SDHS
|
Inadequately controlled trials
|
|---|
|
Major CHD Events
|
0.87 (0.70-1.07)
|
0.93 (0.77-1.11)
|
1.06 (0.86-1.31)
|
0.98 (0.83-1.16)
|
0.64 (0.47-0.87)
|
|
P = 0.19
|
P = 0.40
|
P = 0.59
|
P = 0.80
|
P = 0.004
|
|
I2 = 60%
|
I2 = 48%
|
I2 = 46%
|
I2 = 17%
|
I2 = 38%
|
|
Total CHD Events
|
0.80 (0.65-0.98)
|
0.83 (0.67-1.03)
|
1.02 (0.84-1.23)
|
0.95 (0.83-1.09)
|
0.60 (0.46-0.79)
|
|
P = 0.03
|
P = 0.10
|
P = 0.85
|
P = 0.45
|
P = 0.0002
|
|
I2 = 72%
|
I2 = 71%
|
I2 = 45%
|
I2 = 1%
|
I2 = 59%
|
|
CHD Mortality
|
0.90 (0.70-1.17)
|
0.98 (0.79-1.23)
|
1.13 (0.91-1.40)
|
1.04 (0.85-1.27)
|
0.66 (0.54-0.81)
|
|
P = 0.43
|
P = 0.88
|
P = 0.29
|
P = 0.71
|
P < 0.0001
|
|
I2 = 65%
|
I2 = 39%
|
I2 = 19%
|
I2 = 0%
|
I2 = 11%
|
|
Total Mortality
|
1.00 (0.90-1.10)
|
0.99 (0.86-1.15)
|
1.07 (0.90-1.26)
|
1.03 (0.90-1.17)
|
0.95 (0.82-1.10)
|
|
P = 0.99
|
P = 0.91
|
P = 0.45
|
P = 0.69
|
P = 0.48
|
|
I2 = 26%
|
I2 = 34%
|
I2 = 23%
|
I2 = 0%
|
I2 = 35%
|
- Data are in relative risk and then 95% confidence intervals in parentheses, with P values and I2 values below
