Skip to main content

Table 5 Plasma cholesterol in the diet heart trials

From: The effect of replacing saturated fat with mostly n-6 polyunsaturated fat on coronary heart disease: a meta-analysis of randomised controlled trials

  Experimental group Control group
Baseline (mg/dl) Follow up (mg/dl) Change (mg/dl) Baseline (mg/dl) Follow up (mg/dl) Change (mg/dl)
RCOT [21]    −20    −3
ODHS [22] 296 244 −52 296 285 −11
NDHS [29]a 232 208 −24 229 224 −5
MRCT [23] 272 239 −33 273 269 −4
LAVAT [54] 233 190 −43 234 201 −33
FMHS [43, 57]b   231    270  
SDHS [25] 281 250 −31 282 262 −20
HDAT [31]d 263 249 −14 267 267 0
MCS [26] 205 175 −30 204 203 −1
DART [27] 250 243 −7 250 253 +3
STARS [28] 278 239 −39 273 268 −5
  1. aThe values for NDHS come from a weighted average of the experimental and control groups respectively. bDue to the crossover design used in FMHS, only the values for total cholesterol at the end of each diet period are presented in this table. cThe actual numbers for total plasma cholesterol were not reported in HDAT and the numbers in this table were estimated from graphs reported in the study. This estimation is consistent with Hooper et al. [18], as they estimated from the graph that the average plasma cholesterol of the experimental group was 18 mg/dl lower than the control group at the end of the trial