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Table 5 Plasma cholesterol in the diet heart trials

From: The effect of replacing saturated fat with mostly n-6 polyunsaturated fat on coronary heart disease: a meta-analysis of randomised controlled trials

 

Experimental group

Control group

Baseline (mg/dl)

Follow up (mg/dl)

Change (mg/dl)

Baseline (mg/dl)

Follow up (mg/dl)

Change (mg/dl)

RCOT [21]

  

−20

  

−3

ODHS [22]

296

244

−52

296

285

−11

NDHS [29]a

232

208

−24

229

224

−5

MRCT [23]

272

239

−33

273

269

−4

LAVAT [54]

233

190

−43

234

201

−33

FMHS [43, 57]b

 

231

  

270

 

SDHS [25]

281

250

−31

282

262

−20

HDAT [31]d

263

249

−14

267

267

0

MCS [26]

205

175

−30

204

203

−1

DART [27]

250

243

−7

250

253

+3

STARS [28]

278

239

−39

273

268

−5

  1. aThe values for NDHS come from a weighted average of the experimental and control groups respectively. bDue to the crossover design used in FMHS, only the values for total cholesterol at the end of each diet period are presented in this table. cThe actual numbers for total plasma cholesterol were not reported in HDAT and the numbers in this table were estimated from graphs reported in the study. This estimation is consistent with Hooper et al. [18], as they estimated from the graph that the average plasma cholesterol of the experimental group was 18 mg/dl lower than the control group at the end of the trial