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Table 5 Reported improvements in general health indices following amino acid supplementation

From: Diverse characteristics of the urinary excretion of amino acids in humans and the use of amino acid supplementation to reduce fatigue and sub-health in adults

Symptom index Pre-supplement
Mean (SE)
Post-supplement
Mean (SE)
p value
Chalder Total Fatigue
Chalder Physical fatigue
Chalder Mental Fatigue
13.4 (0.8)
8.3 (0.6)
5.1 (0.3)
8.8 (0.6)
5.5 (0.4)
3.3 (0.2)
<0.0001
<0.001
<0.0001
General Fatigue index 6.9 (1.2) 3.7 (1.0) <0.01
Pain index 4.7 (1.1) 3.9 (1.0) ns
Gastrointestinal index 2.0 (0.6) 2.7 (0.8) ns
Sleep index 10.4 (1.5) 6.6 (1.0) <0.01
Vitality index 6.5 (1.2) 2.2 (0.7) <0.001
  1. Statistical test: Wilcoxon matched pairs test