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Table 2 Prevalence ratios of cardiometaolic risk associated with serum 25(OH)D status in U.S. adults, NHANES 2001–2010

From: Standardized serum 25-hydroxyvitamin D concentrations are inversely associated with cardiometabolic disease in U.S. adults: a cross-sectional analysis of NHANES, 2001–2010

 

HOMAIR

  

MetS

  

CVD Risk (≥15%)

  
 

Yes

No

PR

95% CI

Yes

No

PR

95% CI

Yes

No

PR

95% CI

25(OH)D quartiles (nmol/L)

            

  < 43.4

656

1231

Ref

853

1034

Ref

487

1400

Ref

 43.4–58.6

529

1365

1.02

0.89, 1.17

825

1069

1.04

0.95, 1.13

495

1399

0.86 *

0.76, 0.98

 58.7–74.2

444

1528

0.89

0.76, 1.04

835

1137

1.00

0.90, 1.10

553

1419

0.90

0.79, 1.02

  ≥ 74.3

289

1632

0.70 *

0.59, 0.84

630

1291

0.82 *

0.74, 0.91

430

1491

0.78 *

0.66, 0.91

a Excluding those with self-reported diabetes, CVD, and taking medications (lipid, diabetes, blood pressure)

     

25(OH)D quartiles (nmol/L)

          

  < 43.4

347

890

Ref

361

876

Ref

150

1087

Ref

 43.4–58.6

272

993

0.88

0.73, 1.06

350

915

0.99

0.84, 1.15

139

1126

0.85

0.64, 1.14

 58.7–74.2

192

1076

0.83

0.66, 1.03

330

938

0.97

0.80, 1.17

141

1127

0.77

0.57, 1.04

  ≥ 74.3

108

1145

0.60 *

0.45, 0.81

193

1060

0.65 *

0.52, 0.80

119

1134

0.64 *

0.47, 0.87

  1. Models are adjusted for age, sex, education, ethnicity, season of blood draw, survey cycle, smoking, BMI, total physical activity, vitamin D supplement use, and lipid and anti-hyperglycemic medications
  2. a In sensitivity analyses, models are adjusted for age, sex, education, ethnicity, season of blood draw, survey cycle, smoking, BMI, total physical activity, and vitamin D supplement use
  3. * P < 0.05