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Table 2 Prevalence ratios of cardiometaolic risk associated with serum 25(OH)D status in U.S. adults, NHANES 2001–2010

From: Standardized serum 25-hydroxyvitamin D concentrations are inversely associated with cardiometabolic disease in U.S. adults: a cross-sectional analysis of NHANES, 2001–2010

  HOMAIR    MetS    CVD Risk (≥15%)   
  Yes No PR 95% CI Yes No PR 95% CI Yes No PR 95% CI
25(OH)D quartiles (nmol/L)             
  < 43.4 656 1231 Ref 853 1034 Ref 487 1400 Ref
 43.4–58.6 529 1365 1.02 0.89, 1.17 825 1069 1.04 0.95, 1.13 495 1399 0.86 * 0.76, 0.98
 58.7–74.2 444 1528 0.89 0.76, 1.04 835 1137 1.00 0.90, 1.10 553 1419 0.90 0.79, 1.02
  ≥ 74.3 289 1632 0.70 * 0.59, 0.84 630 1291 0.82 * 0.74, 0.91 430 1491 0.78 * 0.66, 0.91
a Excluding those with self-reported diabetes, CVD, and taking medications (lipid, diabetes, blood pressure)      
25(OH)D quartiles (nmol/L)           
  < 43.4 347 890 Ref 361 876 Ref 150 1087 Ref
 43.4–58.6 272 993 0.88 0.73, 1.06 350 915 0.99 0.84, 1.15 139 1126 0.85 0.64, 1.14
 58.7–74.2 192 1076 0.83 0.66, 1.03 330 938 0.97 0.80, 1.17 141 1127 0.77 0.57, 1.04
  ≥ 74.3 108 1145 0.60 * 0.45, 0.81 193 1060 0.65 * 0.52, 0.80 119 1134 0.64 * 0.47, 0.87
  1. Models are adjusted for age, sex, education, ethnicity, season of blood draw, survey cycle, smoking, BMI, total physical activity, vitamin D supplement use, and lipid and anti-hyperglycemic medications
  2. a In sensitivity analyses, models are adjusted for age, sex, education, ethnicity, season of blood draw, survey cycle, smoking, BMI, total physical activity, and vitamin D supplement use
  3. * P < 0.05