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Table 2 Odds ratios for the association between serum homocysteine and the prevalence of non-alcoholic fatty liver disease

From: Association between homocysteine and non-alcoholic fatty liver disease in Chinese adults: a cross-sectional study

Homocysteine (μmol/L)

N = 7023

OR (95% CI)

Model 1

Model 2

Model 3

Quartiles

 Q1 (<5.1)

1876

1 (Ref)

1 (Ref)

1 (Ref)

 Q2 (5.1 to <7.1)

1815

1.52 (1.30, 1.77)

1.44 (1.18, 1.74)

1.32 (1.04, 1.67)

 Q3 (7.1 to <9.9)

1697

2.38 (2.04, 2.76)

1.90 (1.57, 2.30)

1.75 (1.39, 2.22)

 Q4 (≥9.9)

1815

3.10 (2.67, 3.59)

1.91 (1.57, 2.32)

2.08 (1.61, 2.67)

P for trend

 

<0.001

<0.001

<0.001

Per SD increment

7023

1.47 (1.40, 1.55)

1.18 (1.10, 1.27)

1.25 (1.15, 1.37)

P value

 

<0.001

<0.001

<0.001

  1. Model 1: adjusted for agea; Model 2: further adjusted for gender, body mass index, current smoker, physical activity, education, drinking; Model 3: further adjusted for hypertension, diabetes, uric acid, alanine transaminasea, total bilirubina, albumin, platelet count, triglyceridea, total cholesterol, high-density lipoprotein cholesterol, high-sensitivity C-reactive proteina, creatinine.
  2. Per SD increment represents 1 SD increment of log homocysteine.
  3. aVariables were log transformed before analysis