Meal rich in carbohydrate, but not protein or fat, reveals adverse immunometabolic responses associated with obesity

Table 1 Subject characteristics at baseline

	LIS subjects	OIR subjects	P	Adjusted P *
Age (years)	23.22 ± 0.22	28.56 ± 1.40	0.002
BMI (kg/m²)	22.01 ± 0.18	30.15 ± 0.75	<0.001	<0.001
Waist Circumference (cm)	79.94 ± 0.54	100.78 ± 0.98	<0.001	<0.001
Fasting Blood Glucose (mmol/l)	4.33 ± 0.05	4.68 ± 0.12	0.026	0.459
Fasting Serum Insulin (mU/l)	4.31 ± 0.52	21.04 ± 2.27	<0.001	<0.001
Fasting Total Cholesterol (mmol/l)	5.09 ± 0.27	5.28 ± 0.40	0.697	0.791
Fasting Triglyceride (mmol/l)	0.62 ± 0.07	1.98 ± 0.24	<0.001	0.007
Fasting LDL-Cholesterol (mmol/l)	3.09 ± 0.29	3.20 ± 0.35	0.823	0.730
Fasting HDL-Cholesterol (mmol/l)	1.71 ± 0.08	1.19 ± 0.06	0.001	0.005
Fasting NEFA (mmol/l)^a	0.41 ± 0.04	0.49 ± 0.03	0.037	0.392
Systolic Blood Pressure (mmHg)	110.78 ± 4.07	119.78 ± 2.61	0.084	0.705
Diastolic Blood Pressure (mmHg)	60.56 ± 3.00	71.44 ± 3.18	0.024	0.468
HOMA-IR	0.83 ± 0.10	4.34 ± 0.41	<0.001	<0.001

Data presented as mean ± standard errors of mean. HOMA-IR Homeostatic model assessment-insulin resistance, NEFA Nonesterified fatty acids, LIS Lean insulin sensitive, OIR Obese insulin resistant, *P-value adjusted for age. ^aAnalysis was done on log transformed data-sets

ISSN: 1475-2891