Table 2 Reported anti-cancer activities of plant phenolic acids
From: An overview on the role of dietary phenolics for the treatment of cancers
Phenolic Acid/Phenolic Acid Derivative | Cancers Tested | Cell Lines Used | Reported IC50 (μM) | Reference |
|---|---|---|---|---|
Cinnamic acid | Melanoma | HT-144 | 2400.0 | [56] |
Colon | HT-29 | 1000.0 | [91] | |
Caffeic acid phenyl ester | Prostate | LNCaP | 33.0 | [145] |
Breast | MDA-MB-231 | 14.0 | [146] | |
Hs578T | 8.0 | |||
p-Coumaric acid | Neuroblastoma | N2a | 104.0 | [147] |
Breast | T47D | 474.0 | [148] | |
Colon | SW-620 | 87.0 | [148] | |
Liver | HepG2 | 215.0 | [148] | |
Lung | A549 | 412.0 | [148] | |
Ferulic acid | Prostate | PC-3 | 300.0 | [149] |
LNCaP | 500.0 | |||
Pancreatic | MIA PaCa-2 | 500.0 | [60] | |
Gallic acid | Colon | HCT-15 | 0.5 | [150] |
Breast | MDA-MB-231 | 0.4 | [150] |