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Table 2 Reported anti-cancer activities of plant phenolic acids

From: An overview on the role of dietary phenolics for the treatment of cancers

Phenolic Acid/Phenolic Acid Derivative Cancers Tested Cell Lines Used Reported IC50
(μM)
Reference
Cinnamic acid Melanoma HT-144 2400.0 [56]
Colon HT-29 1000.0 [91]
Caffeic acid phenyl ester Prostate LNCaP 33.0 [145]
Breast MDA-MB-231 14.0 [146]
Hs578T 8.0
p-Coumaric acid Neuroblastoma N2a 104.0 [147]
Breast T47D 474.0 [148]
Colon SW-620 87.0 [148]
Liver HepG2 215.0 [148]
Lung A549 412.0 [148]
Ferulic acid Prostate PC-3 300.0 [149]
LNCaP 500.0
Pancreatic MIA PaCa-2 500.0 [60]
Gallic acid Colon HCT-15 0.5 [150]
Breast MDA-MB-231 0.4 [150]
  1. Table 2 summarizes the anticancer activity of the plant phenolic acids on various cell lines with their IC50 values. The IC50 values varied from nM to mM concentrations