Fig. 5
From: An overview on the role of dietary phenolics for the treatment of cancers
Key processes effected by plant phenolic acids Phenolic compounds are known to modulate the expression of key proteins such as BCL2, BAX, AKT, STAT. While suppressing the oncogenic proteins, phenolic compounds induce the expression of tumor suppressors P53, P21 and P27. As a result, phenolic compounds trigger apoptotic cell death while inhibiting the proliferation and inducing the cell cycle arrest [47]