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Fig. 4 | Nutrition Journal

Fig. 4

From: The association and significance of H3K27me3 and a folate metabolic gene ACat2 in neural tube defects

Fig. 4

a Comparison of the average number and diameter of neurospheres in each group after 5-day culture in serum-free complete medium, suggesting a reduced proliferation of NTD-derived NSCs. Folic acid fortification significantly improved the cell proliferation. *P < 0.05, **P < 0.05, compared with normal controls. #P < 0.05, and ##P < 0.01 compared with NTD group. b Growth curves of NSCs in three groups. Comparison of the average OD value in each group from day 1 to 7 shows lower cell proliferation in NTD-derived NSCs when compared with normal control (P < 0.05). Folic acid fortification significantly improved cell proliferation (P < 0.05)

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