Table 3 Effects of vitamin D therapy in study completed group

Plasma 25(OH)D (nmol/L)

48.2 ± 28.3

105.5 ± 31.7^a

116.2 ± 34.3^a

 < 120 nmol/L (%)

99

69

44

 < 75 nmol/L (%)

84

18

13

 < 25 nmol/L (%)

25

1

1

Plasma total vitamin C (μmol/L)

42.5 ± 27.5

42.9 ± 25.4

42.0 ± 22.8

 Subnormal (%)

40

36

30

Plasma vit D binding protein (μg/mL)

230 ± 64

-

227 ± 63

Serum calcium (mmol/L)

2.33 ± 0.09

2.37 ± 0.11

2.37 ± 0.10

Plasma parathyroid hormone (ng/L)

48.7 ± 23.7

39.7 ± 18.9^b

38.7 ± 18.2^b

Plasma C-reactive protein (mg/L)

20.9 ± 36.8

17.0 ± 22.1

16.7 ± 22.0

Total mood disturbance score

10.4 ± 17.6

10.0 ± 17.1

7.8 ± 17.0

9.4 ± 19.0

Distress Thermometer score

2.1 ± 2.4

1.9 ± 2.2

1.7 ± 2.3

1.6 ± 2.2

ESAS-r

20.3 ± 15.3

20.3 ± 14.0

17.4 ± 13.6

17.7 ± 16.0^c