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Table 2 Statistical findings shown as change from baseline at week 8 and 12

From: Probiotic administration among free-living older adults: a double blinded, randomized, placebo-controlled clinical trial

 

+8 week follow-up

+12 week follow-up

Probiotic

Placebo

ST

Probiotic

Placebo

ST

p-value

p-value

Outcome parameter

Med

Med

tT

UT

Med

Med

tT

UT

GSRS

−0.04 ± 0.6

0 (−0.3–0.3)

−0.08 ± 0.6

−0.1 (−0.30.1)

0.63

0.18

−0.07 ± 0.6

0 (−0.4–0.2)

−0.08 ± 0.6

−0.1 (−0.4–0.2)

0.91

0.42

 Diarrhea

−0.09 ± 0.7

0 (−0.7–0.3)

−0.05 ± 1.0

0 (−0.3–0.3)

0.63

0.89

−0.12 ± 0.9

0 (−0.3–0.3)

−0.05 ± 0.9

0 (−0.3–0)

0.61

0.52

 Indigestion

−0.14 ± 0.9

−0.3 (−0.6–0.3)

−0.15 ± 0.8

0 (−0.5–0)

0.95

0.82

−0.14 ± 0.9

−0.1 (−0.5–0.3)

−0.13 ± 0.7

0 (−0.5–0.3)

0.94

0.89

 Constipation

0.02 ± 1.1

0 (−0.7–0.7)

−0.03 ± 1.0

0 (−0.3–0.3)

0.76

0.46

−0.06 ± 1.1

0 (−0.7–0.3)

−0.10 ± 1.1

0 (−0.3−0.3)

0.82

0.99

 Abdom. pain

−0.07 ± 0.6

0 (−0.3–0.2)

−0.07 ± 0.7

0 (−0.3–0.3)

0.94

0.92

−0.08 ± 0.7

0 (−0.3–0.3)

−0.09 ± 0.7

0 (−0.3–0.3)

0.95

0.86

 Reflux

0.12 ± 0.7

0 (0–0)

−0.13 ± 0.6

0 (0–0)

0.02a

0.02a

−0.02 ± 0.7

0 (0–0)

−0.09 ± 0.5

0 (0–0)

0.45

0.33

EQ-5D

 Index

0 ± 0.1

0 (0–0)

−0.01 ± 0.1

0 (−0.1–0)

0.35

0.23

0 ± 0.1

0 (0–0)

0 ± 0.1

0 (0–0)

0.87

0.79

 VAS

1.89 ± 10.7

0 (−5–5)

0.60 ± 11.5

0 (−5–5)

0.44

0.76

2.88 ± 9.8

0 (−30–0)

3.47 ± 7.7

5 (0–10)

0.66

0.29

HADS

−0.32 ± 3.5

0 (−2–1)

−0.41 ± 2.9

0 (−2–1.3)

0.86

0.45

−0.18 ± 4.4

−0.5 (−2–1)

0.05 ± 5.2

0 (−2–2)

0.77

0.74

 Depression

−0.01 ± 2.1

0 (−1–1)

−0.18 ± 1.9

0 (−1–0)

0.60

0.79

0.04 ± 2.2

0 (−1–1)

−0.01 ± 2.8

0 (−1–1)

0.89

0.91

 Anxiety

−0.31 ± 2.1

0 (−1.3–1)

−0.23 ± 1.9

0 (−1–1)

0.79

0.54

−0.22 ± 2.7

0 (−2–0.13)

0.06 ± 3.0

0 (−1–1)

0.55

0.42

PSS

−0.41 ± 4.9

−1 (−3–2)

−0.24 ± 5.4

0 (−3.8–3)

0.82

0.59

−1.55 ± 4.8

−1 (−5–2)

−1.12 ± 4.4

−1 (−4–1.8)

0.57

0.58

  1. x̅ = Mean ± SD
  2. ST Significance testing between the two treatment groups
  3. tT t-test
  4. UT Mann-Whitney U-test
  5. Med Median (IQR)
  6. asignificant at the 95 confidence level