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Table 3 Effect of intervention with 10 and 25 μg vitamin D3 supplementation on serum ferritin, hemoglobin, serum iron, Transferrin saturation, folic acid and vitamin B12

From: Effect of vitamin D3 supplementation on iron status: a randomized, double-blind, placebo-controlled trial among ethnic minorities living in Norway

 

Baselineb

Final (after 16 weeks)b

Difference in change (95 % CI)a

 

Placebo

10 μg

25 μg

Placebo

10 μg

25 μg

10 μg

25 μg

S-25(OHD) (nmol/L)

29.2 (15.6)

30.7 (20.1)

26.8 (17.1)

27.5 (13.7)

45.9 (18.7)

51.1 (20.1)

17.5 (12.8, 22.1)

25.0 (20.4, 31.9)*

Hemoglobin (g/dL)

13.5 (1.4)

13.8 (1.7)

13.7 (1.4)

13.3 (1.4)

13.5 (1.6)

13.5 (1.6)

-0.07 (-0.27, 0.14)

-0.06 (-0.25, 0.1)

Serum ferritin (ÎĽg/L)

54.4 (63.2)

82.6 (92.5)

55.1 (57.2)

51.0 (57.8)

81.5 (106.2)

55.5 (58.0)

2.98 (-9.3, 15.3)

3.7 (-2.6, 9.9)

Serum iron (ÎĽg/L)

13.0 (5.9)

14.4 (5.9)

14.5 (5.8)

13.5 (6.7)

13.0 (5.5)

15.1 (6.4)

-1.3.(-3.0, 0.5)

-0.6 (-2.3, 1.0)

Transferrin saturation (%)

18.3 (.8.7)

21.7 (9.5)

20.9 (9.3)

18.7 (9.6)

19.3 (8.9)

21.7 (10.2)

-1.3 (-3.9, 1.3)

-1.0 (-3.4, 1.4)

S-Total iron binding capacity (nmol/L)

73.2 (10.8)

68.7 (11.1)

71.7 (11.7)

73.5 (11.1)

69.4 (11.1)

72.1 (12.0)

-0.23 (-2.2, 1.7)

0.2 (-1.6, 2.0)

S-Folic acid (nmol/L)

15.8 (5.8)

15.9 (6.6)

15.2 (7.1)

15.7 (6.1)

14.9 (7.1)

15.1 (7.3)

-0.9 (-2.5, 0.7)

-0.14 (-1.1, 0.8)

S-Vitamin B12 (pmol/L)

339.9 (105.5)

343.9 (116.8)

321.6 (92.7)

337.2 (118.9)

337.6 (132.7)

310 (89.5)

-3.3 (-28.1, 21.5)

-5.5 (-14.8, 3.9)

  1. * p < 0.0001
  2. adifference in change comparing to placebo and adjusted for baseline s-25(OH)D values
  3. bData are mean (standard deviation) unless specified otherwise