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Table 2 Glutamine status of the study population

From: Prevalence of glutamine deficiency in ICU patients: a cross-sectional analytical study

Group

Median plasma GLN level (μmol/L)

medians [25th – 75th percentiles]

P-value

Deficient: <420 μmol/L

Normal: 420 – 930 μmol/L

Supra-normal: >930 μmol/L

n (%)

ICU patients (n = 60)

497 [387 – 644]

 

23 (38.3)

33 (55.0)

4 (6.70)

ICU men (n = 35)

558 [395 – 697]

0.116

12 (34.3)

19 (54.3)

4 (11.4)

ICU women (n = 25)

466 [380 – 543]

 

11 (44.0)

14 (56.0)

–

Admission categories:

 Medical (n = 42)

475 [372 – 627]

0.325**

18 (42.8)

23 (54.8)

1 (2.40)

 Surgical (n = 16)

515 [468 – 782]

 

4 (25.0)

9 (56.2)

3 (18.8)

 Trauma (n = 2)

432 [381 – 432]

 

1 (50.0)

1 (50.0)

–

Specific conditions:b

 HIV+ (n = 8)

562 [375 – 1062]

 

2 (25.0)

5 (62.5)

1 (12.5)

 Liver failure (n = 4)

497 [389 – 643]

 

2 (50.0)

1 (25.0)

1 (25.0)

 Renal failurea (n = 7)

575 [388 – 714]

 

3 (42.9)

4 (57.1)

–

 MOF (n = 4)

355 [310 – 689]

 

3 (75.0)

1 (25.0)

–

 Sepsis (n = 4)

355 [310 – 689]

 

3 (75.0)

1 (25.0)

–

 DM (n = 19)

380 [273 – 500]

 

10 (52.6)

9 (47.4)

–

  1. Non-parametric data reported as median [25th–75thpercentile]
  2. DM diabetes mellitus, GLN glutamine, HIV+ human immunodeficiency virus seroreactive, ICU intensive care unit, MOF multiple-organ failure, n number/ frequency
  3. aPatients not dialysed; bMedian plasma glutamine levels and distribution for certain conditions, that are expected to alter glutamine status
  4. **p-value 0.042 when excluding trauma patients and comparing the medical and surgical patients