Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study

Table 5 ANCOVA and repeated measures ANCOVA analysis for secondary outcomes

	Placebo	Green tea	P-value
FAS analysis	N = 16	N = 17
Total MMSE Score, LSM ± SE	1.04 ± 0.80	0.42 ± 0.77	0.59
LSM difference [95 % CI]	−0.61 [−2.97, 1.74]		0.59
NPI-Q: Total symptom score, LSM ± SE	0.56 ± 0.74	0.23 ± 0.74	0.76
LSM difference [95 % CI]	−0.34 [−2.52, 1.85]		0.76
NPI-Q: Total distress score, LSM ± SE	−0.02 ± 0.64	−0.27 ± 0.64	0.79
LSM difference [95 % CI]	−0.25 [−2.17, 1.67]		0.79
Blood pressure
SBP (mmHg), LSM ± SE	−1.94 ± 4.88	−4.06 ± 4.69	0.76
LSM difference [95 % CI]	−2.12 [−16.46, 12.22]		0.76
DBP (mmHg), LSM ± SE	−1.15 ± 3.71	−2.93 ± 3.57	0.74
LSM difference [95 % CI]	−1.79 [−12.69, 9.12]		0.74
Serum lipid levels
TC (mg/dL), LSM ± SE	0.41 ± 5.72	−10.23 ± 5.50	0.20
LSM difference [95 % CI]	−10.64 [−27.46, 6.18]		0.20
HDL-C (mg/dL), LSM ± SE	0.69 ± 1.75	0.57 ± 1.68	0.96
LSM difference [95 % CI]	−0.12 [−5.26, 5.02]		0.96
LDL-C (mg/dL), LSM ± SE	−4.26 ± 4.92	−14.90 ± 4.73	0.14
LSM difference [95 % CI]	−10.63 [−25.09, 3.83]		0.14
TG (mg/dL), LSM ± SE	−8.80 ± 11.59	−1.32 ± 11.15	0.65
LSM difference [95 % CI]	7.48 [−26.60, 41.57]		0.65
MDA-LDL (U/L), LSM ± SE	21.52 ± 7.21	−1.41 ± 6.93	0.04
LSM difference [95 % CI]	−22.93 [−44.13, −1.73]		0.04
Blood glucose levels
FPG (mg/dL), LSM ± SE	0.75 ± 10.46	4.38 ± 10.06	0.81
LSM difference [95 % CI]	3.63 [−27.13, 34.38]		0.81
HbA1c (%), LSM ± SE	0.16 ± 0.08	0.01 ± 0.07	0.16
LSM difference [95 % CI]	−0.16 [−0.38, 0.07]		0.16

ANCOVA analysis of covariance, CI confidence interval, DBP diastolic blood pressure, FAS full analysis set, FPG fasting plasma glucose, HbA1c hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, LSM least square mean, MDM-LDL malondialdehyde-modified low-density lipoprotein, NPI-Q Neuropsychiatric Inventory Questionnaire, SBP systolic blood pressure, SE standard error, TC total cholesterol, TG triglycerides

ISSN: 1475-2891