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Table 3 ANCOVA and repeated measures ANCOVA analysis

From: Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study

  12 months LOCF
ANCOVA Placebo Green tea P-value Placebo Green tea P-value
FAS N = 16 N = 17   N = 16 N = 17  
Total MMSE-J Score, LSM ± SE 1.04 ± 0.80 0.42 ± 0.77 0.59 0.71 ± 0.71 0.13 ± 0.66 0.56
LSM difference [95 % CI] −0.61 [−2.97, 1.74]   −0.59 [−2.62, 1.45]  
PPS N = 13 N = 13   N = 13 N = 13  
Total MMSE-J Score, LSM ± SE 1.04 ± 0.83 0.46 ± 0.83 0.64 1.03 ± 0.82 0.36 ± 0.79 0.57
LSM mean difference [95 % CI] −0.58 [−3.08, 1.92]   −0.67 [−3.10, 1.76]  
Repeated measures ANCOVA
FAS LSM ± SE LSM difference ± SE P-value
 Placebo 0.75 ± 0.68 −0.33 ± 0.94 0.73
 Green tea 0.42 ± 0.63   
PPS
 Placebo 1.16 ± 0.70 −0.67 ± 1.00 0.51
 Green tea 0.49 ± 0.67   
  1. ANCOVA analysis of covariance, CI confidence interval, FAS full analysis set, LOCF last observation carried forward, LSM least square mean, MMSE-J Mini Mental State Examination, Japanese version, PPS per protocol set, SD standard deviation, SE standard error