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Table 3 ANCOVA and repeated measures ANCOVA analysis

From: Effects of green tea consumption on cognitive dysfunction in an elderly population: a randomized placebo-controlled study

 

12 months

LOCF

ANCOVA

Placebo

Green tea

P-value

Placebo

Green tea

P-value

FAS

N = 16

N = 17

 

N = 16

N = 17

 

Total MMSE-J Score, LSM ± SE

1.04 ± 0.80

0.42 ± 0.77

0.59

0.71 ± 0.71

0.13 ± 0.66

0.56

LSM difference [95 % CI]

−0.61 [−2.97, 1.74]

 

−0.59 [−2.62, 1.45]

 

PPS

N = 13

N = 13

 

N = 13

N = 13

 

Total MMSE-J Score, LSM ± SE

1.04 ± 0.83

0.46 ± 0.83

0.64

1.03 ± 0.82

0.36 ± 0.79

0.57

LSM mean difference [95 % CI]

−0.58 [−3.08, 1.92]

 

−0.67 [−3.10, 1.76]

 

Repeated measures ANCOVA

FAS

LSM ± SE

LSM difference ± SE

P-value

 Placebo

0.75 ± 0.68

−0.33 ± 0.94

0.73

 Green tea

0.42 ± 0.63

  

PPS

 Placebo

1.16 ± 0.70

−0.67 ± 1.00

0.51

 Green tea

0.49 ± 0.67

  
  1. ANCOVA analysis of covariance, CI confidence interval, FAS full analysis set, LOCF last observation carried forward, LSM least square mean, MMSE-J Mini Mental State Examination, Japanese version, PPS per protocol set, SD standard deviation, SE standard error