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Table 4 Composition of the three 3-in-1 TPN admixtures per liter

From: Development and evaluation of a test program for Y-site compatibility testing of total parenteral nutrition and intravenous drugs

 

Olimel® N5E TPNaq/TPN

Kabiven® 1900 kcal TPNaq/TPN

SmofKabiven® 1600 kcal TPNaq/TPN

Lipids total (g)

-/39.2

-/38.2

-/36.9

Olive oil (%)

-/80

-/-

-/25

Soybean oil (%)

-/20

-/100

-/30

MCT (%)

-/-

-/-

-/30

Fish oil (%)

-/-

-/-

-/15

Glucose anhydrous (g)

113.9/112.7

96.5/95.6

124.9/123.3

Amino acids total (g)

32.6/32.3

32.8/32.5

50.1/49.4

Alanine (g)

4.7

4.6

7.0/6.9

Arginine (g)

3.2

3.3/3.2

6.0/5.9

Aspartic acid (g)

0.9

1.0

-

Glutamic acid (g)

1.6

1.6

-

Glycine (g)

2.3/2.2

2.3/2.2

5.5/5.4

Histidine (g)

1.9

2.0

1.5

Isoleucine (g)

1.6

1.6

2.5

Leucine (g)

2.3/2.2

2.3/2.2

3.7

Lysine (g)

2.6/2.5

2.6

3.3

Methionine (g)

1.6

1.6

2.1

Phenylalanine (g)

2.3/2.2

2.3/2.2

2.5

Proline (g)

1.9

2.0

5.6/5.5

Serine (g)

1.3

1.3

3.3/3.2

Taurine (g)

-

-

0.5

Threonine (g)

1.6

1.6

2.2

Tryptophan (g)

0.5

0.5

1.0

Tyrosine (g)

0.1

0.1

0.2

Valine (g)

2.1

2.1

3.1/3.0

Sodium (mmol)

34.6/34.3

30.8/30.6

40.1/39.5

Potassium (mmol)

29.7/29.4

23.2/22.9

30.1/29.6

Magnesium (mmol)

4/3.9

3.9/3.8

5.0/4.9

Calciuma (mmol)

3.5/3.4

1.9/1.9

2.5/2.5

Phosphateb (mmol)

11.9/14.9

6.8/9.7

9.9/12.7

Acetate (mmol)

36.1/35.8

37.6/37.3

104.9/103.5

Chloride (mmol)

44.6/44.1

44.9/44.4

34.7/34.3

Zink (mmol)

-

-

0.04

Sulphate (mmol)

-

3.6/3.8

5.0/4.9

α tocoferol

-

-

n.s

Phospholipids from egg

n.s

n.s

n.s

Glycerol

n.s

n.s

n.s

Sodium oleate

n.s

-

n.s

Water for injections

n.s

n.s

n.s

pH

6.4

5.6

5.6

Tracel®c (ml)

10/9.9

9.7/9.6

13.5/13.4

Soluvit®c (vials)

-/1

-/1

-/1.3

Vitalipid® adultc (ml)

-/9.9

-/9.6

-/13.4

  1. a: calcium chloride as calcium source
  2. b: from sodium glycerophosphate, the emulsion and Vitalipid® adult
  3. c: additives
  4. Excipients other than for pH adjustment are listed
  5. n.s. the quantity is not stated
  6. Source: SmPC from the respective TPN products