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Table 3 Mean plasma and feces concentrations and renal excretion of minerals during the study periods

From: Consequences of a high phosphorus intake on mineral metabolism and bone remodeling in dependence of calcium intake in healthy subjects – a randomized placebo-controlled human intervention study

Parameter

P1000/Ca0

P1000/Ca500

P1000/Ca1000

Plasma calcium [mmol/l]

   

 Placebo

2.36±0.08

2.36ab±0.06

2.36±0.08

 4 weeks

2.34±0.07

2.35a±0.05

2.38±0.08

 8 weeks

2.37±0.09

2.39b±0.07

2.39±0.09

Fecal calcium [mg/g feces]

   

 Placebo

9±5

7±3*

8±3*

 8 weeks

8±4

11±5

12±6

Plasma phosphate [mmol/l]

   

 Placebo

1.20±0.23

1.28±0.16

1.19±0.23

 4 weeks

1.19±0.19

1.24±0.14

1.23±0.20

 8 weeks

1.18±0.23

1.20±0.12

1.23±0.19

Fecal phosphorus [mg/g feces]

   

 Placebo

5±2*

5±2*

6±3*

 8 weeks

8±4

8±4

8±3

Plasma magnesium [mmol/l]

   

 Placebo

0.82±0.06

0.83±0.04

0.82±0.05

 4 weeks

0.82±0.05

0.83±0.04

0.82±0.05

 8 weeks

0.83±0.05

0.84±0.05

0.81±0.05

Urine magnesium [mg/d]

   

 Placebo

113a±41

110±30

106±48

 4 weeks

89b±39

103±36

91±42

 8 weeks

84b±32

103±53

106±56

Fecal magnesium [mg/g feces]

   

 Placebo

2±1

2±1

2±1

 8 weeks

2±1

2±1

2±1

  1. n = 62 for plasma and minerals in urine; n = 61 for fecal minerals; data are expressed as mean ± standard deviation; P1000/Ca0: 1000 mg phosphorus/0 mg calcium; P1000/Ca500: 1000 mg phosphorus/500 mg calcium; P1000/Ca1000: 1000 mg phosphorus/1000 mg calcium; a b mean values within a column with dissimilar superscript lower case letters are significantly different (p ≤ 0.05); * significant different to eight weeks within each group (p ≤ 0.05); effect of time was tested using general linear model with repeated measurements (with pairwise comparisons based on Bonferroni); fecal minerals were tested with paired and with unpaired Students t-Test within each intervention group and between intervention groups, respectively.