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Table 4 Effect of G-hesperidin + caffeine tablets on abdominal fat area

From: Oral intake of a combination of glucosyl hesperidin and caffeine elicits an anti-obesity effect in healthy, moderately obese subjects: a randomized double-blind placebo-controlled trial

Parameter

Group

n

Week-0

Week-12

Change from baseline

Total fat area (cm2)

Placebo

14

301.7 ± 50.6

318.1 ± 50.4

16.3 ± 34.1

GH

15

304.3 ± 41.8

299.7 ± 44.1

−4.6 ± 20.5

GH + Caf 25

15

297.9 ± 54.8

293.7 ± 61.5

−4.2 ± 18.2

GH + Caf 50

15

295.1 ± 53.7

286.7 ± 48.9

−8.4 ± 21.9#

GH + Caf 75

15

310.8 ± 43.9

293.9 ± 45.5

−17.0 ± 31.4##

Visceral fat area (cm2)

Placebo

14

97.2 ± 53.1

102.3 ± 61.9

5.1 ± 25.9

GH

15

97.6 ± 27.7

96.6 ± 27.5

−1.1 ± 15.0

GH + Caf 25

15

107.5 ± 42.3

103.6 ± 40.0

−3.8 ± 14.5

GH + Caf 50

15

108.1 ± 46.1

109.0 ± 46.6

0.9 ± 11.3

GH + Caf 75

15

101.1 ± 28.9

96.5 ± 33.7

−4.5 ± 16.1

Subcutaneous fat area (cm2)

Placebo

14

204.6 ± 59.5

215.8 ± 63.5*

11.2 ± 18.3

GH

15

206.6 ± 45.4

203.1 ± 44.2

−3.5 ± 11.8

GH + Caf 25

15

190.4 ± 59.0

190.1 ± 60.1

−0.4 ± 14.3

GH + Caf 50

15

187.0 ± 48.0

177.7 ± 44.0

−9.3 ± 17.1##

GH + Caf 75

15

209.8 ± 45.4

197.3 ± 44.4*

−12.4 ± 18.7##

  1. GH glucosyl hesperidin 500 mg, Caf 25, 50, 75 caffeine 25 mg, 50 mg, 75 mg
  2. Mean ± SD, *p < 0.05 vs. baseline (week-0), (paired t-test), #p < 0.05, ##p < 0.01 vs. placebo