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Table 5 Comparison in lipid profile (TG, HDL, LDL and VLDL) and HbA1C levels

From: Single-blind, placebo controlled randomised clinical study of chitosan for body weight reduction

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Chitosan (N = 56)

Placebo (N = 30)

P value between groups

TG (mg/dl)

Day 0

145.2 ± 64.35

153.1 ± 76.44

0.753

Day 45

143.7 ± 76.33

160.5 ± 92.92

0.494

Day 90

138.8 ± 63.81

170.3 ± 102.8

0.203

HDL(mg/dl)

Day 0

41.47 ± 7.50

42.87 ± 10.28

0.448

Day 45

44.38 ± 12.01

41.14 ± 9.55

0.285

Day 90

43.17 ± 11.65

42.08 ± 10.74

0.944

LDL (mg/dl)

Day 0

106.9 ± 27.80

107.2 ± 30.39

0.959

Day 45

114.9 ± 42.44* (p = 0.0213)

113.7 ± 38.66

0.746

Day 90

109.9 ± 31.64

115.6 ± 31.93* (p = 0.0266)

0.428

VLDL (mg/dl)

Day 0

29.04 ± 12.87

30.62 ± 15.29

0.746

Day 45

28.74 ± 15.27

32.10 ± 18.59

0.494

Day 90

27.76 ± 12.76

34.07 ± 20.55

0.203

HbA1C (%)

Day 0

5.89 ± 0.83

5.89 ± 0.75

0.912

Day 45

5.72 ± 0.78* (p = 0.0225)

5.80 ± 0.68* (p = 0.0419)

0.661

Day 90

5.74 ± 0.83* (p = 0.0343)

5.88 ± 0.57

0.138

  1. Values are expressed as Mean ± Standard deviation (SD). * = as compared to baseline (Within group comparison). N = Number of patient in each treatment group