Marker | OLIVE | SOYBEAN | OLIVE vs SOYBEAN | ||||
---|---|---|---|---|---|---|---|
 | Visit | N | Mean ± SD | N | Mean ± SD | LSGM Ratio (95 % CI) | P-value |
Cortisol (nmol/L) | Baseline | 214 | 492.98 ± 284.67 | 219 | 499.61 ± 256.24 |  | . |
 | Day 5 | 212 | 371.97 ± 145.68 | 218 | 362.98 ± 130.29 | 1.02 (0.95, 1.1) | 0.5677 |
 | EOT/Day 14 | 82 | 382.37 ± 193.88 | 78 | 395.31 ± 155.08 | 0.9 (0.77, 1.04) | 0.1617 |
C-Reactive protein (mg/L) | Baseline | 214 | 54.56 ± 54.46 | 220 | 56 ± 51.13 |  | . |
 | Day 5 | 211 | 42.33 ± 42.9 | 216 | 47.17 ± 42.98 | 0.95 (0.81, 1.12) | 0.5503 |
 | EOT/Day 14 | 82 | 20.95 ± 34.44 | 78 | 21.92 ± 31.23 | 0.9 (0.62, 1.31) | 0.5785 |
Procalcitonin (ng/mL) | Baseline | 214 | 0.91 ± 1.84 | 219 | 1.19 ± 2.67 |  | . |
 | Day 5 | 212 | 0.36 ± 0.97 | 218 | 0.44 ± 1.29 | 0.98 (0.86, 1.11) | 0.717 |
 | EOT/Day 14 | 82 | 0.15 ± 0.2 | 78 | 0.28 ± 1.1 | 0.88 (0.71, 1.11) | 0.283 |
sICAM-1 (ug/L) | Baseline | 214 | 264.37 ± 127 | 220 | 260.97 ± 128.62 |  | . |
 | Day 5 | 209 | 321.56 ± 158.86 | 217 | 304.41 ± 154.53 | 1.02 (0.94, 1.1) | 0.6462 |
 | EOT/Day 14 | 81 | 337.84 ± 152.58 | 78 | 352.73 ± 197.27 | 0.96 (0.85, 1.08) | 0.4683 |
Interleukin-6 (ng/L) | Baseline | 214 | 143.03 ± 271.46 | 220 | 191.72 ± 705.37 |  | . |
 | Day 5 | 211 | 19.63 ± 57.58 | 218 | 20.11 ± 44.19 | 0.82 (0.69, 0.96) | 0.0173 |
 | EOT/Day 14 | ND | ND | ND | ND | ND | ND |
Malondialdehyde (nmol/L) | Baseline | 214 | 12.46 ± 25.2 | 219 | 11.4 ± 21.93 |  | . |
 | Day 5 | 211 | 13.57 ± 27.65 | 217 | 12.49 ± 23.13 | 0.97 (0.87, 1.08) | 0.5865 |
 | EOT or Day 14 | 82 | 12.65 ± 27.81 | 78 | 10.77 ± 21.68 | 0.86 (0.71, 1.04) | 0.115 |
F2-Isoprostane (ng/mL) | Baseline | 214 | 0.13 ± 0.17 | 219 | 0.11 ± 0.14 |  | . |
 | Day 5 | 211 | 0.19 ± 0.33 | 217 | 0.14 ± 0.2 | 1.13 (0.85, 1.5) | 0.4006 |
 | EOT/Day 14 | 82 | 0.16 ± 0.21 | 78 | 0.18 ± 0.29 | 0.9 (0.58, 1.4) | 0.6502 |