Table 2 Summary of pre-defined outcomes investigated in included systematic reviews
Systematic review refe | Growth indicators (weight, height, stunting, wasting, strength) | Pregnancy/birth outcomes | Iodine status (UIC, goitre rate) | Thyroid function (thyroid hormones (Tg, TSH), thyroid volume, hyper- & hypothyroidism) | Analytical methods to assess iodine status | Cognitive outcomes (performance, mental development score, psychomotor development) | Academic performance, IQ, school absence | Health related quality of life, socioeconomic effects | Health related quality of life, socioeconomic effects Compliance with supplement/fortification, acceptability, costs | Adverse events/morbidity, mortality | Prevalence of micronutrient deficiencies |
|---|---|---|---|---|---|---|---|---|---|---|---|
Taylor et al., 2014 [32] | ✗ | ✗ | ✗ | ✓ | ✗ | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ |
Bougma et al., 2013 [8] | ✗ | ✗ | ✗ | ✗ | ✗ | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ |
Ristić-Medić et al., 2014 [33] | ✗ | ✗ | ✗ | ✓ | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ | ✗ |
Khor & Misra, 2012 [36] | ✗ | ✗ | ✗ | ✗ | ✗ | ✓ | ✓ | ✗ | ✗ | ✗ | ✗ |
Best et al., 2011 [35] | ✓ | ✗ | ✗ | ✗ | ✗ | ✓ | ✓ | ✗ | ✗ | ✓ | ✓ |
Gunnarsdottir & Dahl, 2012 [34] | ✓ | ✓ | ✗ | ✓ | ✗ | ✓ | ✗ | ✗ | ✗ | ✗ | ✗ |
Zhou et al., 2013 [9] | ✓ | ✗ | ✓ | ✓ | ✗ | ✓ | ✗ | ✗ | ✗ | ✓ | ✗ |
Ibrahim et al., 2006 [31] | ✗ | ✗ | ✓ | ✓ | ✗ | ✓ | ✗ | ✗ | ✗ | ✓ | ✗ |
Angermeyr & Clar, 2004 [30] | ✓ | ✗ | ✓ | ✓ | ✗ | ✓ | ✗ | ✓ | ✓ | ✓ | ✗ |
Wu et al., 2002 [21] | ✓ | ✗ | ✓ | ✓ | ✗ | ✓ | ✗ | ✓ | ✓ | ✓ | ✗ |