Skip to main content

Table 1 Baseline demographic and clinical features of the placebo and treatment groups

From: Placebo-controlled randomized clinical trial of fish oil’s impact on fatigue, quality of life, and disease activity in Systemic Lupus Erythematosus

  All Completers
  Placebo (N=25) Fish oil (N=25) Placebo (N=14) Fish oil (N=18)
Demographics     
 Sex, female 22 (88 %) 20 (80 %) 11 (79 %) 14 (78 %)
 Age, years 36.1 [28.6–41.0]a 46.1 [34.7–49.3]a 35.6 [26.3–42.7]a 46.2 [36.8–49.1]a
Ethnicity     
 Hispanic/Latino 11 (44 %) 11 (44 %) 7 (50 %) 8 (44 %)
 Black/African American 13 (52 %) 14 (56 %) 6 (43 %) 10 (56 %)
 White 1 (4 %) 0 (0 %) 1 (7 %) 0 (0 %)
BMI 25.0 [23.4–32.6]a 31.4 [27.5–40.2]a 26.0 [23.7–33.0]a 35.4 [29.0–42.0]a
Rate Your Plate 55 [50–60] 57 [52–63] 56 [50–61] 58 [53–64]
Comorbidities     
 HTN 13 (52 %)a 20 (8O%)a 6 (43 %)a 15 (83 %)a
 DM2 1 (4 %) 6 (24 %) 1 (7 %) 4 (22 %)
 Tobacco Use 5 (20 %) 7 (28 %) 5 (36 %) 6 (33)%
Disease Characteristics     
 SELENA-SLEDAI 8 [2–10] 6 [3–10.5] 4 [0–3.5] 7 [3.5–11.25]
 Disease duration, years 6 [2–10] 6 [3–11] 5.5 [l.8–9.3] 6 [2.8–10.5]
 ACR Criteria, total number 6 [5–7] 5 [5–7] 5 [4–7] 5.5 [5–7]
 Lupus Nephritis 18 (72 %) 17 (68 %) 10 (71 %) 14 (78 %)
Medication     
Prednisone     
 0 mg/day 7 (28 %) 11 (44 %) 5 (36 %) 7 (39 %)
 ≤7.5 mg/day 8 (32 %) 4 (16 %) 5 (36 %) 2 (11 %)
 >7.5 mg/day 10 (40 %) 10 (40 %) 4 (29 %) 9 (50 %)
Hydroxychloroquine 22 (88 %) 22 (88 %) 12 (86 %) 16 (89 %)
Other Immunosuppressants     
 Cyclophosphamide 0 (0 %) 2 (8 %) 0 (0 %) 1 (6 %)
 Mycophenolate 11 (44 %) 11 (44 %) 8 (57 %) 7 (39 %)
 Azathioprine 4 (16 %) 1 (4 %) 2 (14 %) 0 (0 %)
Misc. Medications     
 Statin 5 (20 %) 8 (32 %) 2 (14 %) 7 (39 %)
 ACEI/ARB 16 (64 %) 15 (60 %) 9 (64 %) 12 (67 %)
  1. Characteristics of the fish oil treatment group and olive oil placebo group, for both the intial randomized patient groups (N=50) and the completers (N=32). Data presented as number of patients (%) or median and interquartile range [IQ.R]. Statistically significant differences (p<0.05) comparing fish oil and placebo groups are indicated with a superscript a(a)