Subjects | Measures, New Method, Gold Standard Method (GSM) | Linear Regression Model to Estimate FCAb | Variance, p-value |
---|---|---|---|
265 women | 554 measures, 5-h serum, GSM: average of oral to iv tracer valuesin multiple serum and urine samples collected for 6-10 days | cFCA = 2.3045(Serum) + 0.021953(Weight0.425) (Height0.725) - 0.1735 | R2 0.91 |
≥35 years old [3] | p not provided | ||
30 men | New method at baseline and GSM 6 days later, 5-h serum, GSM: quotient of 5-h oral radioactivity to 3-h iv radioactivity | cFCA = (Serum)0.92373 x (0.385 x (Height0.5285) (Weight0.3721)) | R2 0.90 |
20-60 years old [20] | p < 0.001 | ||
12 men | 24 measures, 5-h serum, GSM: average of oral to iv tracer values in multiple serum and urine samples collected at multiple times, and quotient of 5-h oral radioactivity to 3-h iv radioactivity | Not provided | R2 0.92 |
36 ± 5 years old [21] | p not provided | ||
19 men and women | 19 measures, 4-h serum, GSM: ratio of cumulative recovery of oral to iv tracers in 24-h urine collection | eFCA = ratio of oral calcium tracer to intravenous tracer | R2 0.83 |
≥50 years old [10] | p < 0.001 | ||
22 girls | 31 measures, 4-h serum, GSM: Average of 3 values- oral to iv ratio in 24-h serum, 24-h urine and kinetic model | c,d,fFCA = 1.334(Serum)0.7872BSA1.7132e(-0.01652PMA) | R2 0.94 |
10-15 years old [8] | p < 0.001 | ||
26 women | 129 measures, 4, 5, 6 h serum, GSM: Average of 3 values- oral to iv ratio in 24-h serum, 24-h urine and kinetic model | cFCA = 1.3609(4 h Serum)0.8703BSA0.8708 | R2 0.78 |
19-67 years old [9] | p < 0.001 | ||
cFCA = 1.4065(5 h Serum)0.8437BSA0.7785 | R2 0.78 | ||
p < 0.001 | |||
cFCA = 1.5828(6 h Serum)0.8636BSA0.7142 | R2 0.81 | ||
p < 0.001 |