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Fig. 4 | Nutrition Journal

Fig. 4

From: Effects of a grape-supplemented diet on proliferation and Wnt signaling in the colonic mucosa are greatest for those over age 50 and with high arginine consumption

Fig. 4

Differences in expression of CyclinD1 (a), AXIN2 (b), cMYC (c) and CD133 (d) in participants with high baseline arginine consumption and those with low baseline arginine consumption. Individuals with high arginine intake had significantly higher expression of each of these markers. In those with high arginine intake, grape ingestion led to a statistically significant reduction in CyclinD1 expression to levels seen in those with low arginine intake. Grape intervention did not significantly change the expression of CyclinD1 in participants with low initial arginine intake. *P < 0 · 05; **p < 0 · 01; ***p < 0 · 005

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Nutrition Journal

ISSN: 1475-2891

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