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Table 4 Thyroid hormones, blood pressure and serum lipoproteins at baseline and after the 90-day trial

From: Intake of partially defatted Brazil nut flour reduces serum cholesterol in hypercholesterolemic patients- a randomized controlled trial

Variables Brazil nut (n = 35) Δ T90 – T0 Placebo (n = 42) Δ T90 – T0 P value intragroupa P value intragroupb P value intergroupc
FT3 (pg/mL) 0.1 ± 1.1 −0.1 ± 0.4 NS 0.030* NS
FT4 (ng/dL) 0.1 ± 0.6 −0.1 ± 0.1 NS NS NS
TSH (μUI/mL) 0.2 ± 1.8 −0.2 ± 0.9 NS NS 0.06
SBP (mmHg) 3.5 ± 18.0 −4.0 ± 30.7 NS NS NS
DBP (mmHg) −1.5 ± 13.6 −5.0 ± 15.2 NS 0.020* NS
Total cholesterol (mg/dL) −20.5 ± 61.2 −7.4 ± 44.5 0.020* NS NS
LDL-cholesterol (mg/dL) −6.4 ± 57.9 −6.5 ± 39.5 NS NS NS
HDL-cholesterol (mg/dL) −1.0 ± 5.0 0.8 ± 7.1 NS NS NS
Triglycerides (mg/dL) −49.6 ± 198.2 −0.05 ± 104.1 NS NS NS
Non-HDL cholesterol (mg/dL) −19.5 ± 61.2 −8.2 ± 44.5 0.020* NS NS
Apolipoprotein A-1 (mg/dL) −10.2 ± 26.7 −7.9 ± 27.8 0.040* NS NS
Apolipoprotein B (mg/dL) −5.2 ± 25.9 −5.0 ± 23.4 NS NS NS
ApoB/ApoA-1 ratio 0.02 ± 0.2 −0.06 ± 0.3 NS NS NS
Lp(a) (mg/dl) −0.5 ± 23.7 5.9 ± 18.0 NS 0.02* NS
  1. Mean ± SD. FT3, free triiodothyronine; FT4, free thyroxine; TSH, thyroid stimulating hormone; SBP, systolic blood pressure; DBP, diastolic blood pressure, ApoB, apolipoprotein B; ApoA-1, apolipoprotein A-1; Lp(a), lipoprotein (a)
  2. a Statistical differences in Brazil nut group compared to baseline
  3. b Statistical difference in placebo group compared to baseline
  4. c Statistical differences between group compared at T90
  5. * Significant differences were assumed at P < 0.05
  6. For normally distributed variables (FT3 and FT4), we used a Student’s t test for independent samples and a paired-samples t test to investigate the differences within and between groups, respectively. For non-normally-distributed variables, we used a Mann–Whitney U test and a Wilcoxon Signed Ranks test to assess the differences within and between groups, respectively