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Table 1 Characteristics of included studies of coffee in relation to risk of hip fracture

From: Effect of coffee intake on hip fracture: a meta-analysis of prospective cohort studies

Author

Year

Country

Period

Duration (years)

Cases

Participants

Mean age or age range (years)

Assessment of coffee consumption

Hip fracture ascertainment

Highest vs. lowest category of coffee consumption

RR (95% CI)

Adjustments

Cummings S R

1995

America

1986-1990

4

192

9516

≥65

Frequency questionaire

Radographs

≥1 vs. never

1.20 (1.00 -1.50)

Fractures and calcaneal bone density

Hallstrom H

2013

America

1987-2008

22

3871

14738

≥50

Frequency questionaire

Hospital registers

≥4 vs. < 1

0.88 (0.78 -1.00)

Age, body mass index, height, total energy intake, and dietary intakes of calcium, vitamin D, retinol, protein, phosphorous, potassium, and alcohol, vitamin D supplementation, tea consumption, educational level, physical activity level, smoking status, previous fracture, Charlson comorbidity index, living condition (living alone or not), nulliparity, cortisone use, and hormone replacement therapy.

Hansen S A

2000

America

1986-1992

6.5

275

34703

55-69

Frequency questionaire

Self-reportd

≥4 vs. ≤ 0.5

0.92 (0.62 -1.36)

Age, alcohol intake, calcium intake, estrogen-replacement therapy, smoking, physical activity, body mass index, caloric intake, and waist hip rate

Hernandez-Avila M

1991

America

1980-1986

6

59

84484

34-59

Frequency questionaire

Self-reported

≥4 vs.never

3.35 (1.32 -8.49)

Age, Quetelet index, menopause status, oestrogen-replacement therapy, calcium intake, alcohol intake

Jokinen H

2010

Finland

1997-2007

10

21

1222

72

Frequency questionaire

Medical records

>5 vs. <5

2.58 (1.01 -6.56)

Body mass index, physical activity, calcium intake, smoking, alcohol use, and cardiovascular disease.

Kiel D

1990

America

1971-1982

12

135

17,256

76.5

Frequency questionaire

Medical records and self-reported

>2 vs. ≤ 2

1.82 (1.09 -3.05)

Sex, age, Framingham examination number, metropolitan relative weight, postmenopausal oestrogen use, smoking, alcohol consumption

Meyer H E

1997

Norway

1977-1991

11.4

212

19938

56.5

Frequency questionaire

Medical records or discharge letters

≥9 vs. <2

1.94(0.96 -3.91)

Age, body height, body mass index, self-reported physical activity at work and during leisure time, diabetes mellitus, disability pension, marital status, and smoking

for women

1.04 ( 0.37 -2.94)

for men

Trimpou P

2010

Sweden

1974-2003

30

451

7495

46-56

Frequency questionaire

Hospital discharge register

>5 vs.never

0.55 (0.42 -0.73)

Age, physical activity, smoking, stature, occupation, alcohol abuse, intercurrent stroke, dementia, serum cholesterol concentrations, body mass index, diabetes mellitus, psychological stress, systolic blood pressure

van Lenthe F J

2011

Netherlands

1991-2003

13

192

16578

>55

Frequency questionaire

Hospital admission database

≥3 vs. never

0.75 (0.42 -1.36)

Father’s occupation, adult occupation, education, income proxy