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Table 6 Changes in serum n-6 and n-3 fatty acids concentrations in corn oil and flaxseed oil periods

From: Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study

   Corn oil period Flaxseed oil period
   0 week 4 week 12 week 0 week 4 week 12 week
Linoleic acid (μg/ml) 907.2 ± 19.4 1004.7 ± 29.2* 908.8 ± 30.5 868.7 ± 23.3 909.6 ± 17.7 792.0 ± 20.6
γ-linolenic acid (μg/ml) 15.9 ± 1.6 15.8 ± 2.5 12.0 ± 1.5 12.7 ± 1.4 12.1 ± 1.4 10.5 ± 1.2
Eicosadienoic acid (μg/ml) 7.1 ± 0.3 7.0 ± 0.3 6.2 ± 0.3 6.5 ± 0.4 6.3 ± 0.4 5.3 ± 0.2*†
Dihomo-γ-linolenic acid (μg/ml) 44.4 ± 2.7 40.7 ± 2.7 36.0 ± 2.8* 39.4 ± 2.2 33.8 ± 2.3 31.2 ± 2.0*
Arachidonic acid (μg/ml) 201.4 ± 10.7 187.3 ± 10.2 164.7 ± 7.6* 188.5 ± 10.1 172.7 ± 9.7 163.5 ± 9.4*
Docosatetraenoic acid (μg/ml) 5.8 ± 0.5 5.3 ± 0.4 4.1 ± 0.2* 4.8 ± 0.3 4.5 ± 0.4 3.8 ± 0.3*
alpha-linolenic acid (μg/ml) 33.4 ± 2.4 30.7 ± 2.6 24.2 ± 1.8* 27.5 ± 2.5 92.8 ± 7.4*† 86.1 ± 8.7*†
Eicosapentaenoic acid (μg/ml) 77.5 ± 16.1 67.9 ± 10.8 49.6 ± 7.9* 77.7 ± 16.6 91.3 ± 15.6 71.0 ± 10.7
Docosapentaenoic acid (μg/ml) 24.9 ± 2.7 22.7 ± 2.2 17.9 ± 1.7* 22.5 ± 2.4 24.5 ± 1.9 19.6 ± 1.4
Docosahexaenoic acid (μg/ml) 138.1 ± 16.5 130.8 ± 14.7 107.4 ± 12.9* 132.9 ± 16.3 123.3 ± 12.9 102.8 ± 9.8*
n-6/n-3 ratio   5.1 ± 0.5 5.6 ± 0.5 6.5 ± 0.6* 5.3 ± 0.6 3.8 ± 0.3*† 3.9 ± 0.3*†
  1. Values are means ± SE, n = 15.
  2. *; p <0.05 vs. baseline, repeated-measures ANOVA with Bonferroni correction, †; p <0.05 vs. corn oil, paired t test.