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Table 6 Changes in serum n-6 and n-3 fatty acids concentrations in corn oil and flaxseed oil periods

From: Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study

  

Corn oil period

Flaxseed oil period

  

0 week

4 week

12 week

0 week

4 week

12 week

Linoleic acid

(μg/ml)

907.2 ± 19.4

1004.7 ± 29.2*

908.8 ± 30.5

868.7 ± 23.3

909.6 ± 17.7†

792.0 ± 20.6†

γ-linolenic acid

(μg/ml)

15.9 ± 1.6

15.8 ± 2.5

12.0 ± 1.5

12.7 ± 1.4

12.1 ± 1.4

10.5 ± 1.2

Eicosadienoic acid

(μg/ml)

7.1 ± 0.3

7.0 ± 0.3

6.2 ± 0.3

6.5 ± 0.4

6.3 ± 0.4

5.3 ± 0.2*†

Dihomo-γ-linolenic acid

(μg/ml)

44.4 ± 2.7

40.7 ± 2.7

36.0 ± 2.8*

39.4 ± 2.2

33.8 ± 2.3†

31.2 ± 2.0*

Arachidonic acid

(μg/ml)

201.4 ± 10.7

187.3 ± 10.2

164.7 ± 7.6*

188.5 ± 10.1

172.7 ± 9.7†

163.5 ± 9.4*

Docosatetraenoic acid

(μg/ml)

5.8 ± 0.5

5.3 ± 0.4

4.1 ± 0.2*

4.8 ± 0.3†

4.5 ± 0.4†

3.8 ± 0.3*

alpha-linolenic acid

(μg/ml)

33.4 ± 2.4

30.7 ± 2.6

24.2 ± 1.8*

27.5 ± 2.5

92.8 ± 7.4*†

86.1 ± 8.7*†

Eicosapentaenoic acid

(μg/ml)

77.5 ± 16.1

67.9 ± 10.8

49.6 ± 7.9*

77.7 ± 16.6

91.3 ± 15.6†

71.0 ± 10.7†

Docosapentaenoic acid

(μg/ml)

24.9 ± 2.7

22.7 ± 2.2

17.9 ± 1.7*

22.5 ± 2.4

24.5 ± 1.9

19.6 ± 1.4

Docosahexaenoic acid

(μg/ml)

138.1 ± 16.5

130.8 ± 14.7

107.4 ± 12.9*

132.9 ± 16.3

123.3 ± 12.9

102.8 ± 9.8*

n-6/n-3 ratio

 

5.1 ± 0.5

5.6 ± 0.5

6.5 ± 0.6*

5.3 ± 0.6

3.8 ± 0.3*†

3.9 ± 0.3*†

  1. Values are means ± SE, n = 15.
  2. *; p <0.05 vs. baseline, repeated-measures ANOVA with Bonferroni correction, †; p <0.05 vs. corn oil, paired t test.