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Table 2 Mean difference in changes of the studied parameters after placebo or nutraceutical treatment

From: Short-term effects of a combined nutraceutical of insulin-sensitivity, lipid level and indexes of liver steatosis: a double-blind, randomized, cross-over clinical trial

N.40

Mean difference in changes

95% CI

P

 

Lower

Upper

∆ Weight (kg)

−0,2

−0.9

1.1

0.534

∆ Body Mass Index (kg/m2)

−0,1

−0.8

1.0

0.687

∆ Waist Circumference (cm)

−0,6

−1.1

1.2

0.432

∆ Systolic Blood Pressure (mmHg)

0,2

−0.6

0.8

0.326

∆ Diastolic Blood Pressure (mmHg)

0,8

−0.1

1.3

0.091

∆ Pulse Pressure (mmHg)

−0,5

−0.9

0.2

0.084

∆ Mean Arterial Pressure (mmHg)

0,5

−0.2

0.9

0.102

∆ Heart Rate (bpm)

−0,1

−1.3

1.3

0.518

∆ Total Cholesterol (mg/dL)

−19,5

−61.4

−9.3

<0.001

∆ LDL-C (mg/dL)

−15,4

−45.3

−2.7

<0.001

∆ Triglycerides (mg/dL)

−21,4

−64.3

−1.1

<0.001

∆ HDL-C (mg/dL)

0,3

−0.1

2.1

0.054

∆ Non HDL-C (mg/dL)

−19,7

−62.2

−3.0

<0.001

∆ Fasting Plasma Glucose (mg/dL)

−0,1

−9.4

7.6

0.433

∆ Insulin (μU/ml)

−1

−1.1

−0.1

0.018

∆ HOMA-IR

−0,3

−0.5

−0.1

<0.001

∆ GOT (U/L)

−0,3

−0.7

0.9

0.681

∆ GPT (U/L)

−7,8

−11.4

−0.9

0.027

∆ Serum Uric Acid (mg/dL)

−2,4

−3.7

1.4

0.349

∆ Creatinine (mg/dL)

−0,5

−0.9

0.8

0.441

∆ Lipid Accumulation Product

−10,4

−44.5

−0.3

0.002

∆ Hepatic Steatosis Index

1,3

−0.1

2.9

0.068

  1. Acronyms: LDL-C: LDL cholesterol, HDL-C: HDL cholesterol, Non HDL-C: non HDL cholesterol, HOMA-IR: homeostatic model assessment of insulin resistance, GOT: glutamic oxaloacetic transaminase, GPT: glutamate-pyruvate transaminase.