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Table 2 Summary of outcomes of clinical trials utilizing SR for diabetes and weight control

From: Salacia reticulata (Kothala himbutu) revisited; a missed opportunity to treat diabetes and obesity?

  

FBS (mg/dl) Pre intervention

Post intervention

HbA1C (%) Pre intervention

Post intervention

BMI (Kg/m2) Pre intervention

Post intervention

Kajimoto et al. (2000) [28]

Group A SRE

140 + − 14.6

125.7 + −18.6*

6.6 + − 0.2

6.52 + − 0.67

24.1 + − 4.4

23.5 + − 3.8*

 

Placebo

125.7 + − 18.6 (CO)

131.6 + − 22.4*

6.59 + − 0.65

23.5 + − 3.8 (CO)

23.5 + − 3.8

 

Group B SRE

139 + − 12.2

120 + − 16*

6.6 + − 0.2

6.46 + − 0.38*

22.8 + − 0.8

22.3 + − 2.4*

 

Placebo

 

139 + −20.4

6.60 + − 0.4

22.7 + − 2.5

Jayawardena et al. (2005) [29]

SR

-

-

6.8 + −0.9

6.29 + − 1.02*

-

-

 

Placebo

-

-

6.8 + − 0.9

6.65 + − 1.04

-

-

Shivaprasad et al. (2013) [30]

SR Root bark

115.2 + − 1.35

98.4 + −2.96*

-

-

-

-

 

SR Leaves

115.5 + − 1.43

95.9 + − 2.5* (At 6 weeks)

    
 

Placebo

116.1 + − 1.76

109.2 + − .5 (At 6 weeks)

-

-

-

-

Ofner et al. (2013) [31]

SR (Group B)

-

-

-

-

31.2 + − 4.7

29.3 + −4.5*

 

Exercise only (Group A)

-

-

-

-

30.0 + − 5.3

29.4 + − 9.7

  1. *denotes a statistical significance of P <0.05.
  2. CO: at crossover.