Folate, Vitamin B12 and Homocysteine status in the post-folic acid fortification era in different subgroups of the Brazilian population attended to at a public health care center

Table 6 Predictors of Hcy levels in the elderly, children and pregnant women

Groups	Independent variables	β	R ²	P
Elderly
	Folate	−4.594	0.0441	p < 0.001
	Vitamin B12	−0.044	0.0324	p < 0.001
	Gender (male)	52.785	0.1622	p < 0.001
	Age	3.219	0.0716	p < 0.001
	RFC1 (AG x AA)	−26.995	0.0192	0.011
	(GG x AA)	−11.736
Children
	Vitamin B12	−0.023	0.0782	0.011
Pregnant women
	Folate	−4.556	0.0750	p < 0.001

Multiple linear regression analysis with stepwise criteria. Independent variables: age, gender (male versus female), smoking, hypertension, diabetes, dyslipidemia, BMI, polymorphisms (RFC1 A80G, GCPII C1561T e MTHFR C677T), folate and vitamin B12. In pregnant women, the analysis was adjusted for gestational stage.

ISSN: 1475-2891