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Table 3 Changes in blood parameters prior to, at two and six months of treatment

From: Zinc and vitamin A supplementation fails to reduce sputum conversion time in severely malnourished pulmonary tuberculosis patients in Indonesia

Variables Groups
  Zinc Vitamin A Zinc+ Vit A Placebo
Plasma CRP (mg/L), median (IQR)     
   0 month 25.7 (13.7-38.8) 27.9 (11.5-42.1) 29.1 (12.6-43.0) 30.9 (13.3-47.4)
   2 month 4.6 (1.4-13.8) ‡ 4 (1-14.3)‡ 4.2 (1.3-15.5) ‡ 6.4 (1.5-14.6) ‡
   6 month 1.3 (0.5-2.7)‡ 1.5(0.6-3.3)‡ 1.1 (0.5-4.4) ‡ 1.7 (0.9-40)‡
Serum albumin (g/dL), mean ± SD     
   0 month 3.8 ± 0.84 4.0 ± 0.75 4.0 ±0.96 3.8 ± 0.83
   2 month 4.5 ± 0.68‡ 4.3 ± 0.88† 4.4 ± 0.74 4.4 ± 0.78‡
   6 month 4.6 ± 0.52‡ 4.6 ± 0.72‡ 4.7 ± 0.62‡ 4.6 ± 0.52‡
Leukocytes(cells/mm3),median (IQR)     
   0 month 9300 (7575-13000) 9750 (7775-11575) 10200 (7475-12250) 9750 (7000-2225)
   2 month 6700 (5400-8100)‡ 6600 (5600-8050)‡ 7500 (5500-8875)‡ 7300 (5900-9100)‡
   6 month 6000 (5100-7000)‡ 6900(5275-8100)‡ 6800 (5850-7800)‡ 6800(5800-8100)‡
ESR (mm),median (IQR)     
   0 month 73.0 (48.0-99.5) 59.5 (40.0-88.5) 62.0 (36.0-92.0) 75.0 (42.0-109.0)
   2 month 28 (16-40)‡ 31 (18-40)‡ 30 (17.3-38.8)‡ 28 (16-45)‡
   6 month 11 (4-28)‡ 14 (8-28.8)‡ 12 (6-28)‡ 11 (8-28)‡
Hemoglobin(g/dL), mean ± SD     
   0 month 11.2 ± 2.7 11.6 ± 2.4 11.6 ± 2.5 11.0 ± 2.5
   2 month 12.5 ± 2.78‡ 12.6 ± 2.55‡ 13.18 ± 2.48‡ 12.12 ± 2.43‡
   6 month 12.8 ± 2.3‡ 13.0 ± 2.2‡ 13.3 ± 2.2‡ 12.8 ± 2.3‡
Plasma zinc(μmol/L), mean ± SD     
   0 month 11.6 ± 2.2 11.9 ± 3 12.1 ± 3.0 11.8 ± 2.4
   2 month 11.7 ± 2.43† 11.6 ± 1.83‡ 12.5 ± 2.33‡ 11.7 ± 2.33‡
   6 month 13.1 ± 1.92† 12.5 ± 2.1† 12.8 ± 2.9† 12.6 ± 1.7 3‡
Plasma retinol(μmol/L), median (IQR)     
   0 month 0.7(0.5-1.0) 0.7(0.5-1.5) 0.7(0.4-1.1) 0.7 (0.5-1)
   2 month 1.2 (1-1.6)a 1.5(1-2)ab 1.3 (1-1.9)‡ 1.2 (0.9-1.6)b
   6 month 1.4 (1.1-1.9)† 1.6 (1.2-2.0)‡ 1.6 (1.2-1.9) 1.4 (1.0-1.8)‡
  1. SD = standard deviation, IQR = interquartile range, *significant difference of proportion between groups (chi-squared, p < 0.05), significant changes from baseline p < 0.05† and p < 0.001‡, ab significant changes between group (One-way ANOVA, p < 0.05)