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Table 3 Pneumococcal IgG types 18C and 23F - Comparisons between ResistAid(TM) and Placebo Groups

From: Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers

 

Day 0

Mean ± SD

Day 51

Mean ± SD

Day 72

Mean ± SD

Change

Day 0-51

Change

Day 0-72

Type 18C

     

ResistAidâ„¢ (n = 21)

1.49 ± 3.00

9.57 ± 7.96

9.10 ± 7.53

8.08 ± 7.12

7.61 ± 6.81

Placebo (n = 24)

0.72 ± 1.35

5.06 ± 5.80

4.93 ± 5.26

4.34 ± 5.10

4.22 ± 4.69

Comparison (p-value)

0.061

0.006

0.008

0.033

0.012

Type 23F

     

ResistAidâ„¢ (n = 21)

0.74 ± 0.93

7.07 ± 7.41

7.02 ± 7.31

6.33 ± 7.36

6.28 ± 7.17

Placebo (n = 24)

1.08 ± 1.87

4.32 ± 4.62

4.55 ± 5.23

3.24 ± 4.28

3.46 ± 4.24

Comparison (p-value)

0.059

0.002

0.041

0.001

0.003

  1. Levels of antibody subtypes 18C and 23F in the ResistAid™ and placebo groups are given as means (μg/dl) ± standard deviations on Days 0, 51 and 72 and changes from Day 0. Inoculation with the 23-valent pneumococcal vaccine took place on Day 30. P-values are comparisons between groups and comparisons of changes from Day 0 in the two groups.