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Table 4 Sustained Phase: Mean Change in Outcome Measures after Six Weeks of Treatment

From: Daily egg consumption in hyperlipidemic adults - Effects on endothelial function and cardiovascular risk

Variable Egg (n = 36) Egg substitute (n = 36) p-value
Endothelial Function    
Flow Mediated Dilatation (%)    
   Baseline 5.6 ± 3.9 5.8 ± 3.9 0.78
   6 Weeks 5.3 ± 4.1 6.9 ± 4.0  
   Change -0.1 ± 1.5 (P = 0.80) 1.0 ± 1.2 (P < 0.01) <0.01
   Adjusted change† -0.2 ± 1.3 (P = 0.35) 0.9 ± 1.4 (P < 0.01) < 0.01
Stimulus adjusted response measure    
   Baseline 0.08 ± 0.10 0.06 ± 0.06 0.39
   6 Weeks 0.08 ± 0.11 0.09 ± 0.09  
   Change 0.01 ± 0.05 (P = 0.54) 0.03 ± 0.06 (P < 0.01) 0.07
Lipid Panel    
Total Cholesterol (mg/dL)    
   Baseline 244 ± 24 244 ± 24 1.00
   6 Weeks 239 ± 27 227 ± 27  
   Change -5 ± 21 (P = 0.10) -18 ± 18 (P < 0.01) < 0.01
Low Density Lipoprotein (mg/dL)    
   Baseline 168 ± 17 168 ± 17  
   6 Weeks 165 ± 24 154 ± 24  
   Change -2 ± 19 (P = 0.30) -14 ± 20 (P < 0.01) 0.01
High Density Lipoprotein (mg/dL)    
   Baseline 52 ± 15 52 ± 15 1.00
   6 Weeks 51 ± 14 50 ± 13  
   Change -1 ± 11 (P = 0.53) -2 ± 10 (P = 0.15) 0.63
Triglycerides (mg/dL)    
   Baseline 132 ± 52 132 ± 52 1.00
   6 Weeks 118 ± 47 116 ± 50  
   Change -14 ± 37 (P = 0.02) -18 ± 43 (P = 0.03) 0.83
Total Cholesterol to High Density Lipoprotein Ratio    
   Baseline 5.0 ± 1.3 5.0 ± 1.3 1.00
   6 Weeks 5.0 ± 1.2 4.8 ± 1.3  
   Change -0.06 ± 0.66 (P = 0.54) -0.21 ± 0.82 (P = 0.11) 0.38
Body composition    
Weight (kg)    
   Baseline 81 ± 19 81 ± 19 1.00
   6 Weeks 82 ± 18 82 ± 18  
   Change 0.4 ± 2.3 (P = 0.33) 0.7 ± 2.4 (P = 0.08) 0.52
Body Mass Index (kg/m2)    
   Baseline 29.2 ± 4.5 29.2 ± 4.5 1.00
   6 Weeks 29.3 ± 4.3 29.5 ± 4.5  
   Change 0.2 ± 0.8 (P = 0.13) 0.4 ± 0.9 (P = 0.04) 0.56
  1. Values are mean ± SD; p-value obtained from ANOVA for repeated measurements except otherwise stated; p-values in parenthesis indicate within-group p-values; *p-value obtain from student ttest; Change = 6 Weeks - Baseline; † obtained from generalized linear models, controlling for age, blood pressure, LDL and BMI