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Table 1 Effect of germinated brown rice on AOM-induced ACF formation in male Sprague Dawley rats

From: Germinated brown rice (GBR) reduces the incidence of aberrant crypt foci with the involvement of β-catenin and COX-2 in azoxymethane-induced colon cancer in rats

   No. of ACF containing  
Treatment ACF/colon 1 crypt 2 crypts 3 crypts 4 or more crypts Total aberrant crypt
AOM + basal diet
(G1)
41.50
± 3.008
16.00
± 0.730
15.67
± 1.520
4.00
± 0.894
5.50
± 1.310
81.30
± 7.745
AOM + basal diet + 2.5 g/kg of GBR
(G2)
28.60
± 1.720a
12.20
± 1.241
10.60
± 1.208a
2.20
± 0.200
3.40
± 0.678
53.60
± 3.970a
AOM + basal diet + 5 g/kg of GBR
(G3)
25.50
± 2.327a
12.00
± 2.160
9.50
± 0.646a
2.75
± 0.250
1.25
± 0.479a
44.25
± 2.750a
AOM + basal diet +10 g/kg of GBR
(G4)
24.40
± 1.806a
10.40
± 1.123a
8.40
± 0.927a
2.20
± 0.374
2.80
± 0.860
44.00
± 4.159a
Basal diet alone (G5) 0 0 0 0 0 0
  1. Values are expressed as mean ± SEM. Mean with the a superscript are significant p < 0.05 as compared to positive control, G1