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Table 5 Lipid and Inflammatory Measures at Week 0 and Week 40

From: Efficacy of a meal replacement diet plan compared to a food-based diet plan after a period of weight loss and weight maintenance: a randomized controlled trial

Measurement Week MD Group
Mean ± SD
Within Group
Δ p-value
Week FB Group
Mean ± SD
Within Group
Δ p-value
Between Group
Δ p-value
Total 0 (n = 39) 191.2 ± 39.5 p = 0.154 0 (n = 40) 187.5 ± 43.0 p = 0.003 p = 0.632
Cholesterol (mg/dl) 40 (n = 23) 182 ± 32.5   40 (n = 20) 183.0 ± 45   
HDL 0 (n = 39) 52.0 ± 16.0 p = 0.509 0 (n = 40) 51.8 ± 18.0 p = 0.029 p = 0.86
(mg/dl) 40 (n = 23) 53.2 ± 12.2   40 (n = 20) 49.6 ± 11.8   
LDL 0 (n = 39) 117.3 ± 31.8 p = 0.088 0 (n = 40) 108.8 ± 32.0 p = 0.099 p = 0.811
(mg/dl) 40 (n = 23) 107.1 ± 28.5   40 (n = 20) 104.1 ± 31.1   
VLDL 0 (n = 38) 21.9 ± 13.0 p = 0.614 0 (n = 37) 27.9 ± 17.9 p = 0.38 p = 0.648
(mg/dl) 40 (n = 23) 21.7 ± 14.0   40 (n = 20) 29.3 ± 16.4   
Triglycerides 0 (n = 39) 109.2 ± 63.7 p = 0.516 0 (n = 40) 134.7 ± 86.8 p = 0.391 p = 0.579
(mg/dl) 40 (n = 23) 107.7 ± 70.1   40 (n = 20) 137.4 ± 101.2   
CRP 0 (n = 38) 5.7 ± 4.8 p < 0.0001 0 (n = 39) 7.1 ± 9.4 p = 0.008 p = 0.886
(mg/L) 40 (n = 23) 2.6 ± 2.2   40 (n = 20) 3.5 ± 3.6   
ULP 0 (n = 44) 6.1 ± 2.2 p = 0.006 0 (n = 44) 5.5 ± 1.7 p = 0.837 p = 0.038
(micromol/g creatinine) 40 (n = 23) 4.9 ± 2.4   40 (n = 20) 5.4 ± 2.5   
  1. Δ = Change from baseline to 40 weeks.
  2. = Secondary outcomes.