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Table 6 Mean organ-to-brain weight ratios of male and female rats that consumed PGX® for 90 days

From: The safety of PolyGlycopleX® (PGX®) as shown in a 90-day rodent feeding study

Organ Control 1.25% 2.5% 5.0%
Males     
   Heart 0.72 ± 0.06 0.74 ± 0.04 0.71 ± 0.05 0.72 ± 0.07
   Kidneys (paired) 1.56 ± 0.11 1.47 ± 0.09 1.47 ± 0.17 1.45 ± 0.09
   Liver 5.63 ± 0.58 5.64 ± 0.43 5.87 ± 0.96 5.90 ± 0.37
   Spleen 0.41 ± 0.07 0.38 ± 0.04 0.37 ± 0.03 0.40 ± 0.03
   Testes (paired) 2.04 ± 0.12 2.05 ± 0.12 2.02 ± 0.18 2.05 ± 0.15
   Adrenals (paired) 0.032 ± 0.005 0.030 ± 0.005 0.031 ± 0.006 0.031 ± 0.003
   Epididymides 0.795 ± 0.056 0.810 ± 0.090 0.833 ± 0.86 0.873 ± 0.073
   Thymus 0.160 ± 0.029 0.181 ± 0.029 0.161 ± 0.017 0.148 ± 0.042
Females     
   Heart 0.52 ± 0.06 0.52 ± 0.05 0.50 ± 0.03 0.49 ± 0.04
   Kidneys (paired) 1.03 ± 0.06 0.99 ± 0.08 0.97 ± 0.11 0.95 ± 0.06
   Liver 3.56 ± 0.39 3.57 ± 0.39 3.42 ± 0.34 3.47 ± 0.26
   Spleen 0.35 ± 0.06 0.35 ± 0.06 0.34 ± 0.05 0.31 ± 0.03
   Uterus 0.37 ± 0.09 0.41 ± 0.13 0.35 ± 0.10 0.35 ± 0.09
   Adrenals (paired) 0.039 ± 0.007 0.038 ± 0.003 0.039 ± 0.007 0.039 ± 0.005
   Ovaries 0.066 ± 0.014 0.069 ± 0.015 0.074 ± 0.029 0.072 ± 0.021
   Thymus 0.124 ± 0.025 0.133 ± 0.032 0.134 ± 0.028 0.135 ± 0.028