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Table 5 Mean organ weights of male and female rats that consumed PGX® for 90 days

From: The safety of PolyGlycopleX® (PGX®) as shown in a 90-day rodent feeding study

Organ Control 1.25% 2.5% 5.0%
Males     
   Brain 1.98 ± 0.12 1.97 ± 0.06 2.00 ± 0.12 1.99 ± 0.10
   Heart 1.42 ± 0.13 1.46 ± 0.09 1.41 ± 0.11 1.43 ± 0.10
   Kidneys (paired) 3.09 ± 0.23 2.90 ± 0.20 2.91 ± 0.23 2.89 ± 0.21
   Liver 11.11 ± 1.10 11.12 ± 0.89 11.62 ± 1.29 11.76 ± 0.68
   Spleen 0.81 ± 0.15 0.76 ± 0.08 0.75 ± 0.07 0.81 ± 0.07
   Testes (paired) 4.03 ± 0.32 4.04 ± 0.27 4.01 ± 0.25 4.08 ± 0.19
   Adrenals (paired) 0.063 ± 0.008 0.058 ± 0.0101 0.061 ± 0.0101 0.061 ± 0.004
   Epididymides 1.571 ± 0.123 1.596 ± 0.188 1.663 ± 0.219 1.739 ± 0.137
   Thymus 0.314 ± 0.045 0.358 ± 0.061 0.322 ± 0.049 0.294 ± 0.080
Females     
   Brain 1.79 ± 0.14 1.88 ± 0.07 1.92 ± 0.13 1.88 ± 0.07
   Heart 0.93 ± 0.09 0.97 ± 0.08 0.96 ± 0.07 0.93 ± 0.06
   Kidneys (paired) 1.84 ± 0.09 1.86 ± 0.18 1.85 ± 0.13 1.78 ± 0.10
   Liver 6.34 ± 0.58 6.70 ± 0.84 6.51 ± 0.40 6.50 ± 0.38
   Spleen 0.62 ± 0.09 0.66 ± 0.13 0.64 ± 0.07 0.58 ± 0.07
   Uterus 0.65 ± 0.16 0.77 ± 0.23 0.67 ± 0.19 0.66 ± 0.18
   Adrenals (paired) 0.069 ± 0.009 0.071 ± 0.006 0.073 ± 0.010 0.073 ± 0.009
   Ovaries 0.118 ± 0.024 0.129 ± 0.029 0.140 ± 0.048 0.135 ± 0.042
   Thymus 0.219 ± 0.0411 0.250 ± 0.061 0.254 ± 0.049 0.253 ± 0.054
  1. 1Mean and standard deviation for 9 animals