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Table 5 Mean organ weights of male and female rats that consumed PGX® for 90 days

From: The safety of PolyGlycopleX® (PGX®) as shown in a 90-day rodent feeding study

Organ

Control

1.25%

2.5%

5.0%

Males

    

   Brain

1.98 ± 0.12

1.97 ± 0.06

2.00 ± 0.12

1.99 ± 0.10

   Heart

1.42 ± 0.13

1.46 ± 0.09

1.41 ± 0.11

1.43 ± 0.10

   Kidneys (paired)

3.09 ± 0.23

2.90 ± 0.20

2.91 ± 0.23

2.89 ± 0.21

   Liver

11.11 ± 1.10

11.12 ± 0.89

11.62 ± 1.29

11.76 ± 0.68

   Spleen

0.81 ± 0.15

0.76 ± 0.08

0.75 ± 0.07

0.81 ± 0.07

   Testes (paired)

4.03 ± 0.32

4.04 ± 0.27

4.01 ± 0.25

4.08 ± 0.19

   Adrenals (paired)

0.063 ± 0.008

0.058 ± 0.0101

0.061 ± 0.0101

0.061 ± 0.004

   Epididymides

1.571 ± 0.123

1.596 ± 0.188

1.663 ± 0.219

1.739 ± 0.137

   Thymus

0.314 ± 0.045

0.358 ± 0.061

0.322 ± 0.049

0.294 ± 0.080

Females

    

   Brain

1.79 ± 0.14

1.88 ± 0.07

1.92 ± 0.13

1.88 ± 0.07

   Heart

0.93 ± 0.09

0.97 ± 0.08

0.96 ± 0.07

0.93 ± 0.06

   Kidneys (paired)

1.84 ± 0.09

1.86 ± 0.18

1.85 ± 0.13

1.78 ± 0.10

   Liver

6.34 ± 0.58

6.70 ± 0.84

6.51 ± 0.40

6.50 ± 0.38

   Spleen

0.62 ± 0.09

0.66 ± 0.13

0.64 ± 0.07

0.58 ± 0.07

   Uterus

0.65 ± 0.16

0.77 ± 0.23

0.67 ± 0.19

0.66 ± 0.18

   Adrenals (paired)

0.069 ± 0.009

0.071 ± 0.006

0.073 ± 0.010

0.073 ± 0.009

   Ovaries

0.118 ± 0.024

0.129 ± 0.029

0.140 ± 0.048

0.135 ± 0.042

   Thymus

0.219 ± 0.0411

0.250 ± 0.061

0.254 ± 0.049

0.253 ± 0.054

  1. 1Mean and standard deviation for 9 animals