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Table 3 Changes in WOMAC Scores at baseline and at the end of the trial Between and Within Groups (ITT-LOCF)

From: A natural mineral supplement provides relief from knee osteoarthritis symptoms: a randomized controlled pilot trial

Variable Pain
Baseline
Pain
End
Pain baseline – pain end Stiffness
Baseline
Stiffness
End
Stiffness baseline – stiffness end Activity
Baseline
Activity
End
Activity baseline – activity end Composite
Baseline
Composite
End
Composite baseline – composite end
PBO 50.0 52.9 -2.9 40.4 46.3 -5.9 49.4 56.4 -7.0 48.8 54.8 -6.1
SD 22.9 21.4 19.9 17.4 25.3 18.3 23.1 24 18.4 21.8 22.7 17.6
Sig.*    NS    NS    NS    NS
A 56.8 74.3 -17.5 44.4 65 -20.6 58.8 72.4 -13.5 57.3 72.2 -14.9
SD 15.8 17.6 22.7 17 17.5 26.1 16.2 16.8 21.3 15.3 16.6 21.4
Sig.*    .0.003    0.002    0.01    0.006
GS 60.6 72.9 -12.6 51.3 61.8 -10.5 60.1 70.7 -10.6 59.4 70.2 -10.9
SD 14.8 17.6 16.3 13.8 19.8 24.0 13.9 18.4 15.4 13.2 17.6 15.6
Sig.*    0.003    NS    0.008    0.007
G+A 67.2 69.1 -1.9 57.8 64.1 -6.3 63 68.6 -5.6 63.4 68.3 -4.9
SD 13.3 16.9 14.0 15.7 17.6 17.7 8.7 13.1 11.0 8.1 12.9 101
Sig.*    NS    NS    NS    NS
p(ANCOVA) 0.039#   0.009 0.013#   NS NS#   NS NS#   NS
  1. *Sig. = significance by within group paired t-test; 2-tailed; ANCOVA comparison between groups with baseline measure as covariate.
  2. # = ANCOVA comparison between groups showing any differences at baseline for these parameters.