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Table 3 Results of the physical health dimension of the SF-36v2 in 16 evaluable subjects

From: Effect of a natural extract of chicken combs with a high content of hyaluronic acid (Hyal-Joint®) on pain relief and quality of life in subjects with knee osteoarthritis: a pilot randomized double-blind placebo-controlled trial

Study groups and time points SF-36v2 scores, mean (SD)
  Physical functioning Role-physical Bodily pain General health
Hyal-Joint® (n = 8)     
   Baseline 31.8 (9.5) 36.1 (9.3) 33.7 (5.5) 48.5 (9.9)
   Week 4 34.9 (7.1) 42.2 (7.2) 39.5 (4.5) 46.0 (10.8)
   Week 8 34.2 (11.0) 42.8 (6.8) 44.9 (10.1) 51.3 (9.2)
   Change baseline vs week 4 3.1 (5.2) 6.1 (3.9) 5.8 (4.7) -2.5 (8.8)
P value 0.137 0.003 0.011 0.444
   Change baseline vs week 8 2.4 (5.2) 6.8 (7.8) 11.1 (9.6) 2.8 (9.7)
P value 0.239 0.045 0.013 0.439
Placebo (n = 8)     
   Baseline 25.5 (7.5) 41.6 (8.3) 36.4 (4.8) 46.5 (10.4)
   Week 4 30.5 (9.7) 41.9 (11.6) 39.5 (5.6) 44.4 (8.4)
   Week 8 33.1 (9.0) 44.6 (9.3) 38.6 (5.4) 48.4 (7.9)
   Change baseline vs week 4 5.0 (5.1) 0.3 (5.6) 3.2 (3.7) -2.1 (4.9)
P value 0.028 0.884 0.045 0.267
   Change baseline vs week 8 7.6 (5.2) 3.1 (5.0) 2.2 (4.4) 1.9 (5.5)
P value 0.004 0.129 0.199 0.360