Table 3 Results of the physical health dimension of the SF-36v2 in 16 evaluable subjects
Study groups and time points | SF-36v2 scores, mean (SD) | |||
|---|---|---|---|---|
Physical functioning | Role-physical | Bodily pain | General health | |
Hyal-Joint® (n = 8) | ||||
Baseline | 31.8 (9.5) | 36.1 (9.3) | 33.7 (5.5) | 48.5 (9.9) |
Week 4 | 34.9 (7.1) | 42.2 (7.2) | 39.5 (4.5) | 46.0 (10.8) |
Week 8 | 34.2 (11.0) | 42.8 (6.8) | 44.9 (10.1) | 51.3 (9.2) |
Change baseline vs week 4 | 3.1 (5.2) | 6.1 (3.9) | 5.8 (4.7) | -2.5 (8.8) |
P value | 0.137 | 0.003 | 0.011 | 0.444 |
Change baseline vs week 8 | 2.4 (5.2) | 6.8 (7.8) | 11.1 (9.6) | 2.8 (9.7) |
P value | 0.239 | 0.045 | 0.013 | 0.439 |
Placebo (n = 8) | ||||
Baseline | 25.5 (7.5) | 41.6 (8.3) | 36.4 (4.8) | 46.5 (10.4) |
Week 4 | 30.5 (9.7) | 41.9 (11.6) | 39.5 (5.6) | 44.4 (8.4) |
Week 8 | 33.1 (9.0) | 44.6 (9.3) | 38.6 (5.4) | 48.4 (7.9) |
Change baseline vs week 4 | 5.0 (5.1) | 0.3 (5.6) | 3.2 (3.7) | -2.1 (4.9) |
P value | 0.028 | 0.884 | 0.045 | 0.267 |
Change baseline vs week 8 | 7.6 (5.2) | 3.1 (5.0) | 2.2 (4.4) | 1.9 (5.5) |
P value | 0.004 | 0.129 | 0.199 | 0.360 |