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Table 2 List of possible causes and treatments for bipolar disorder including specific doses as well as supplementary information

From: Nutritional therapies for mental disorders

Mental Disorder

Proposed Cause

Treatment

References

Bipolar Disorder

Food allergies

Avoid foods that elicit an allergic response

[76, 77]

 

Caffeine

Avoid coffee and other caffeinated beverages

[78]

 

Inhibition of lithium from alkalizing agents

Avoid alkalizing agents like bicarbonates

[79]

 

Vitamin B6 deficiency

100–200 milligrams/day

[72, 80]

 

Vitamin B12 deficiency

300–600 mcirograms/day

[71, 81–83]

 

Vitamin C deficiency

1–3 grams taken as divided doses

[84–86]

 

Folate deficiency

200 micrograms/day

[9, 13, 71, 82, 83, 87, 88]

 

Choline deficiency

10–30 grams of phosphatidyl form in divided doses

[73, 89]

 

Omega-3 or -6 deficiency

500–1000 milligrams/day

[10, 11, 21, 39, 74, 75, 90–94]

 

Phenylalanine deficiency

Initially 500 milligrams/day; can increase to 3–4 grams/day

[95, 96]

 

Tryptophan deficiency

50–200 milligrams taken as divided doses

[97–100]

 

S-Adenosyl-L-Methionine (SAM) deficiency

800 milligrams

[101–103]

 

Melatonin deficiency

3–6 milligrams at 9 pm

[104–106]

 

Phosphatidylserine deficiency

100 milligrams with food

[107]