Phellodendron and Citrusextracts benefit cardiovascular health in osteoarthritis patients: a double-blind, placebo-controlled pilot study

Table 5 Lipid Levels.

Group	Time 0	4 weeks	8 weeks	%Δ 0–4 wks	%Δ 0–8 wks
OP
Cholesterol	195.7	-13.30 ± 12.20	-14.80 ± 16.83	-7.2*	-8.0*
HDL	69.8	0.86 ± 0.95	-0.87 ± 5.72	1.2	-1.3
LDL	89.3	-12.64 ± 16.49	-13.01 ± 16.89	-13.8*	-14.2*
Triglycerides	124.8	-7.85 ± 10.5	-4.58 ± 7.82	-6.3*	-3.7*
OT
Cholesterol	194.5	-31.6 ± 20.68	-43.45 ± 20.96	-15.8*	-21.7*
HDL	69.7	3.37 ± 10.64	8.33 ± 13.25	4.8	11.8*
LDL	105.9	-32.99 ± 23.61	-47.47 ± 22.24	-31.0*	-44.6*
Triglycerides	118.4	-16.52 ± 21.78	-21.57 ± 22.97	-13.9*	-18.1*
NP
Cholesterol	197.3	-9.83 ± 12.91	14.88 ± 13.37	-4.8	-7.3*
HDL	63.6	-0.36 ± 6.91	4.3 ± 4.88	-0.6	6.8
LDL	123.6	-8.82 ± 17.36	-18.02 ± 14.38	-7.1	-14.5*
Triglycerides	86.0	-3.27 ± 2.38	-5.83 ± 8.30	-3.8*	-6.8
NT
Cholesterol	197.0	-14.77 ± 15.51	-19.45 ± 16.26	-7.3*	-9.7*
HDL	67.3	0.50 ± 4.58	2.63 ± 2.96	0.74	3.9*
LDL	116.0	-12.80 ± 15.86	-19.51 ± 16.89	-11.0*	-16.8*
Triglycerides	88.7	-12.33 ± 6.50	-12.82 ± 6.03	-13.9*	-14.5*

*Significant P values < 0.05.
OP = overweight placebo, OT = overweight treatment, NP = normal weight placebo and NT = normal weight treatment.
Values at the start of the study (Time 0) listed in the first column are means of data from individuals. Mean changes after 4 weeks and 8 weeks are listed in the second and third columns as ± Standard Deviation. A negative value indicated a decrease in value and a positive number represents an increase in value. %Δ values are percent mean change in value between time 0 and either 4 or 8 weeks. Values* are significant P-value comparisons (< 0.05) between initial values at Time 0 and either 4 weeks or 8 weeks.

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