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Table 7 Comparison between nuclear receptor and COX-2 mRNA expression in healthy colorectal mucosa from patients with BMI < 25 or with BMI ≥ 25

From: The effect of body weight on altered expression of nuclear receptors and cyclooxygenase-2 in human colorectal cancers

Gene

BMI < 25

BMI ≥ 25

pa

 

n

Median

Range

n

Median

Range

 

PPARγ

9

1.00

(10.65–3.19)

11

0.95

(0.35–2.11)

n.s.(0.882)

PPARδ

9

1.35

(0.69–2.34)

11

1.28

(0.72–2.00)

n.s.(0.882)

RXRα

9

0.76

(0.37–1.20)

11

0.64

(0.20–1.25)

n.s.(0.095)

RARα

9

1.09

(0.69–1.85)

11

1.17

(0.72–1.88)

n.s.(0.824)

RARβ

9

1.53

(0.52–2.49)

11

1.30

(0.12–5.39)

n.s.(0.370)

RARγ

9

1.21

(0.76–3.68)

11

1.60

(0.49–9.52)

n.s.(0.230)

COX-2

9

1.11

(0.51–3.48)

11

2.93

(0.44–6.75)

0.002

  1. Statistical analyses were performed using Mann-Whitney test
  2. n.s. not significant
  3. a Mann-Whitney test