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Table 2 Nuclear receptor and COX-2 mRNA expression in colorectal tumors

From: The effect of body weight on altered expression of nuclear receptors and cyclooxygenase-2 in human colorectal cancers

Gene

n

Normal colon mucosa

Tumor tissue

pa

  

Median

Range

Median

Range

 

PPARγ

20

0.96

(0.35–3.19)

1.04

(0.28–4.71)

n.s.

PPARδ

20

1.30

(0.69–2.34)

1.54

(0.40–4.96)

0.001

RXRα

20

0.75

(0.20–1.25)

0.95

(0.21–3.49)

<0.001

RARα

20

1.13

(0.69–1.88)

1.44

(0.38–3.93)

<0.001

RARβ

20

1.42

(0.12–5.39)

2.20

(0.18–10.82)

<0.001

RARγ

20

1.37

(0.49–9.52)

3.42

(0.83–15.80)

<0.001

COX-2

20

1.50

(0.44–6.75)

12.80

(0.50–560.5)

<0.001

  1. Statistical analyses were performed using Wilcoxon-test
  2. n.s. not significant
  3. a Wilcoxon test