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Table 3 response to tetanus and typoid vaccination

From: Effect of a mixture of micronutrients, but not of bovine colostrum concentrate, on immune function parameters in healthy volunteers: a randomized placebo-controlled study

 

Control (n = 31)

Colostrum (n = 33)

Micronutrients (n = 31)

Colostrum+Micronutrients (n = 35)2

Tetanus toxoid-specific IgG levels in serum (IU/L)

   Baseline

126 (90.2 – 175)

154 (111 – 212)

147 (105 – 206)

138 (101 – 189)

   Week 8

2141 (1040 – 4407)

4074 (2024 – 8200)

3368 (1625 – 6982)

5131 (2579 – 10208)

   Week 10

3138 (1713 – 5748)

4728 (2629 – 8500)

4206 (2282 – 7753)

5330 (3013 – 9431)

S. typhi Ty21a LPS-specific IgG in serum (E.U/mL)

   Baseline3

3.37 (2.24 – 5.07)

3.93 (2.64 – 5.84)

5.39 (3.54 – 8.20)

6.48 (4.40 – 9.52)

   Week 83

12.6 (9.02 – 17.6)

16.5 (12.0 – 22.8)

19.5 (13.9 – 27.5)

21.6 (15.7 – 29.6)

   Week 103

10.7 (7.67 – 14.8)

14.0 (10.1 – 19.2)

16.7 (11.9 – 23.4)

18.4 (13.5 – 25.2)

S. typhi Ty21a LPS-specific IgA in serum (E.U./mL)

   Baseline

1.21 (0.85 – 1.72)

1.07 (0.76 – 1.51)

1.36 (0.95 – 1.95)

1.43 (1.03 – 1.99)

   Week 8

2.70 (1.89 – 3.86)

3.40 (2.40 – 4.81)

3.49 (2.42 – 5.04)

3.73 (2.65 – 5.24)

   Week 10

1.80 (1.29 – 2.52)

1.86 (1.35 – 2.57)

2.24 (1.59 – 3.14)

2.20 (1.60 – 3.01)

  1. 1 values are expressed as lsmeans (95% CI).
  2. 2 n = 34 in serum at week 8, n = 33 for saliva at week 8.
  3. 3Micronutrient group (Micronutrients group and Colostrum + Micronutrients group) is significantly different from non-micronutrient group (Control group and Colostrum group) (P < 0.05).