Table 4 Effects of control and soy foods on serum and urinary markers of bone metabolism

IGF-I (nmol/L)

17.9 ± 1.4^b

20.5 ± 1.4^a

20.2 ± 1.4^a

13.3 ± 1.2^c

16.8 ± 1.2^ab

16.8 ± 1.2^ab

0.023

< 0.001

0.693

IGFBP3 (ng/mL)

3833 ± 133

3934 ± 133

3904 ± 135

3442 ± 120^b

3751 ± 120^a

3622 ± 121^a

0.087

0.005

0.252

Osteocalcin (ng/mL)

8.3 ± 2.1^b

13.9 ± 2.1^a

16.2 ± 2.2^a

8.9 ± 1.9^b

17.4 ± 2.0^a

18.1 ± 2.0^a

0.365

< 0.001

0.671

BSAP (U/L)

19.8 ± 1.2^c

23.3 ± 1.2^b

25.3 ± 1.2^a

19.8 ± 1.1^c

22.6 ± 1.1^b

24.9 ± 1.1^a

0.796

< 0.001

0.818

ALP (U/L)

57.4 ± 3.0^c

65.9 ± 3.0^b

74.0 ± 3.1^a

56.6 ± 2.7^c

69.1 ± 2.7^b

74.3 ± 2.8^a

0.798

< 0.001

0.499

Urine

Dpd (nmol/mmol creatinine)

5.3 ± 0.4

5.3 ± 0.4

4.9 ± 0.4

5.2 ± 0.3

5.4 ± 0.3

5.1 ± 0.3

0.888

0.234

0.744