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Table 5 Correlation between CCS content in tissues and liver and plasma Cu concentration, Cp activity and liver and erythrocyte SOD1 activity1,2

From: Copper Chaperone for Cu/Zn Superoxide Dismutase is a sensitive biomarker of mild copper deficiency induced by moderately high intakes of zinc

Tissue CCS Diet Groups3, n = 60 Diet Groups4, n = 48
  Liver Cu Plasma Cu Cp Liver SOD1 Erythrocyte SOD1 Liver Cu Plasma Cu Cp Liver SOD1 Erythrocyte SOD1
Liver -0.746
(<0.001)
-0.816
(<0.001)
-0.787
(<0.001)
-0.418
(<0.005)
-0.464
(<0.001)
-0.597
(<0.001)
-0.649
(<0.001)
-0.615
(<0.001)
-0.222
(NSD)
-0.221
(NSD)
Erythrocyte -0.633
(<0.001)
-0.618
(<0.001)
-0.590
(<0.001)
-0.268
(<0.05)
-0.332
(<0.01)
-0.425
(<0.005)
-0.308
(<0.05)
-0.297
(<0.05)
-0.001
(NSD)
0.001
(NSD)
WBC -0.7685
(<0.001)
-0.8135
(<0.001)
-0.7695
(<0.001)
-0.4955
(<0.005)
-0.5825
(<0.001)
-0.4746
(<0.05)
-0.5596
(<0.005)
-0.5436
(<0.005)
-0.0696
(NSD)
-0.4296
(<0.05)
  1. 1 Pearson's correlation coefficients.
  2. 2 P values are in parentheses; NSD = no statistical difference.
  3. 3 Diet groups Zn-30, Zn-60, Zn-120, Zn-240, and Cu-D.
  4. 4 Diet groups Zn-30, Zn-60, Zn-120, and Zn-240.
  5. 5 n = 35.
  6. 6 n = 28.