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Table 2 Tissue Cu concentrations and SOD1 activity 1,2

From: Copper Chaperone for Cu/Zn Superoxide Dismutase is a sensitive biomarker of mild copper deficiency induced by moderately high intakes of zinc

Diet Group

Liver Cu

(ÎĽg/g dry weight)

Kidney Cu

(ÎĽg/g dry weight)

Mucosal Cu

(ÎĽg/g dry weight)

Liver SOD1 Activity

U/mg protein

Erythrocyte SOD1 Activity

U/mg Hb

Zn-30

17.50 ± 0.87a

23.08 ± 1.07a

9.66 ± 0.25ab

27.39 ± 1.90a

53.21 ± 2.21a

Zn-60

16.08 ± 0.57ab

21.28 ± 1.04ab

9.21 ± 0.26ab

26.91 ± 1.15a

52.61 ± 1.97a

Zn-120

14.70 ± 1.07b

20.57 ± 0.85b

8.64 ± 0.51a

24.31 ± 1.84a

48.58 ± 1.45a

Zn-240

16.38 ± 0.65ab

21.74 ± 0.82ab

9.78 ± 0.36b

25.25 ± 1.44a

49.06 ± 1.61a

Cu-D

9.45 ± 0.82c

15.84 ± 0.32c

5.50 ± 0.49c

19.40 ± 1.76b

41.81 ± 1.55b

  1. 1 Values in a column without a common letter differ, P < 0.05.
  2. 2 Values are means ± SEM, n = 12/diet group.