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Table 4 Antioxidant parameters in healthy volunteers after regular consumption of native or dealcoholized red wine

From: Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial [ISRCTN68505294]

  RW DRW Controls
Subjects, n 24 25 25
Parameter    
TPP, mg CE/L    
   Baseline 15.6 ± 1.6 15.6 ± 2.1 15.5 ± 1.4
   6 wk 16.4 ± 1.4* 16.0 ± 2.0 15.3 ± 2.2
TEAC, mmol/L    
   Baseline 1.47 ± 0.06 1.44 ± 0.08 1.46 ± 0.08
   6 wk 1.45 ± 0.04 1.42 ± 0.07 1.43 ± 0.07
Vitamin C, mg/dL    
   Baseline 1.30 ± 0.28 1.43 ± 0.36 1.48 ± 0.29
   6 wk 1.35 ± 0.26 1.42 ± 0.39 1.57 ± 0.28
α-Tocopherol, mg/dL    
   Baseline 11.3 ± 3.0 11.2 ± 2.6 11.2 ± 2.9
   6 wk 11.3 ± 3.0 11.5 ± 2.7 11.0 ± 2.7
Uric acid, mg/dL    
   Baseline 4.7 ± 1.2 4.4 ± 1.1 4.4 ± 1.2
   6 wk 4.9 ± 1.2 4.5 ± 0.9 4.7 ± 1.5*
Albumin, g/dL    
   Baseline 4.2 ± 0.4 4.3 ± 0.4 4.2 ± 0.4
   6 wk 4.3 ± 0.4 4.1 ± 0.6 4.2 ± 0.5
Bilirubin, mg/dL    
   Baseline 0.68 ± 0.28 0.68 ± 0.33 0.64 ± 0.33
   6 wk 0.61 ± 0.35 0.59 ± 0.27* 0.62 ± 0.35
TM0, arbitrary units    
   Baseline 2,18 ± 0,56 1,97 ± 0,56 2,22 ± 0,79
   6 wk 1,88 ± 0,48* 2,05 ± 0,70 1,95 ± 0,49
TM300, arbitrary units    
   Baseline 1,02 ± 0,69 0,87 ± 0,72 0,95 ± 0,54
   6 wk 0,96 ± 0,49 0,92 ± 0,65 1,18 ± 0,50
  1. Amounts ingested daily for 6 weeks were 200 mL red wine (RW) or 175 mL dealcoholized red wine (DRW). Control subjects did not receive any study drink.
  2. TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM0: Tail Moment in untreated cells (endogenous DNA strand breaks);
  3. TM300: Tail Moment in cells treated with 300 μM H2O2 for 20 min (exogenous DNA strand breaks)
  4. Values are means ± SD
  5. *Values different from baseline, P < 0.05 by Wilcoxon signed rank test