Figure 1

DNA strand breaks in peripheral leukocytes after single ingestion of native or dealcoholized red wine. A) Tail Intensity in untreated cells (endogenous DNA strand breaks) B) Tail Intensity in cells treated with 300 μM H₂O₂ for 20 min (exogenous DNA strand breaks)Amounts of study drinks ingested were 200 mL red wine (RW), 175 mL dealcoholized red wine (DRW) or 200 mL water (Controls) The box represents the distribution falling between the 25^th and 75^th percentiles, with the median as the horizontal line within the box. The whiskers connect the largest and smallest values not categorized as outliers or extreme values, which are represented by single data points. *, ** Values different from baseline, *P < 0.05; ** P < 0.01 by Wilcoxon signed rank test ^a,bValues marked with identical letters differ between groups, P < 0.01 by Mann-Whitney U-test