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Table 3 Bone metabolism biomarkers in 3 stages of the study (n = 15).

From: Assessment of soy phytoestrogens' effects on bone turnover indicators in menopausal women with osteopenia in Iran: a before and after clinical trial

Variables*

At the start

6 weeks

12 weeks

P value†

TALP (IU/l)

237.5 ± 85.4**

300.4 ± 294.1

281.3 ± 80.5

<0.05

OC (ng/ml)

11.4 ± 4.8

12.7 ± 5.7

11.5 ± 4.8

NS ††

IGFBP3 (ng/ml)

3304.6 ± 728.6

3221.6 ± 534.4

3103.9 ± 639.8

NS

DPD (nmol/mmol)

7 ± 1.2

5.9 ± 1.1

5.1 ± 2.1

<0.05

C-TX (ng/ml)

0.79 ± 0.49

0.8 ± 0.4

0.8 ± 0.3

NS

ITCP (μg/l)

4.6 ± 0.9

4.3 ± 0.9

5.9 ± 1.1

NS

  1. * TALP: Total alkaline phosphatase (IU/l); OC: Osteocalcin (ng/ml); IGFBP3: Insulin like growth factor binding protein 3 (ng/ml); DPD: Deoxypyridinoline (nmol/mmol); C-TX: C-Telopeptides (ng/ml); ITCP: Carboxy terminal telopeptides of type I collagen (μg/l)
  2. ** Mean ± SD
  3. † To analyze changes in 3 stages, repeated measurement analysis was utilized.
  4. †† significant level was set at below 5 percent (P < 0.05).
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Nutrition Journal

ISSN: 1475-2891

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